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The effect of stimulants on sleep characteristics in children with attention deficit/hyperactivity disorder
Objective: To investigate the effects of stimulant medications on subjective and objective sleep characteristics of children with attention deficit/hyperactivity disorder (ADHD) compared with control children. Methods: An observational study in the sleep clinic and the community. Children with chara...
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| Published in: | Sleep medicine 2003-07, Vol.4 (4), p.309-316 |
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| Main Authors: | , , , , , , |
| Format: | Article |
| Language: | English |
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| container_end_page | 316 |
| container_issue | 4 |
| container_start_page | 309 |
| container_title | Sleep medicine |
| container_volume | 4 |
| creator | O'Brien, Louise M Ivanenko, Anna Crabtree, Valerie McLaughlin Holbrook, Cheryl R Bruner, Jennifer L Klaus, Carrie J Gozal, David |
| description | Objective: To investigate the effects of stimulant medications on subjective and objective sleep characteristics of children with attention deficit/hyperactivity disorder (ADHD) compared with control children.
Methods: An observational study in the sleep clinic and the community. Children with characteristics of ADHD, both stimulant-medicated (
n=53), and non-medicated (
n=34), together with control children (
n=53) completed a sleep habits questionnaire prior to undergoing full overnight polysomnographic assessment.
Results: Medicated and non-medicated ADHD subjects were reported to have more sleep disturbances compared with controls. Both groups of ADHD children also demonstrated decreased REM sleep percentage compared with controls (
P=0.006 for ADHDmed;
P=0.02 for ADHDnon). However, the use of stimulant medication (
n=53) was not associated with differences in subjective sleep quality or objective sleep measures, compared to ADHD children not taking any medication (
n=34;
P=n.s.).
Conclusions: Despite the high prevalence of reported sleep disturbance in children with ADHD, stimulant medication appears to have minimal effects on subjective and objective sleep characteristics in children with reported ADHD. |
| doi_str_mv | 10.1016/S1389-9457(03)00071-6 |
| format | article |
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Methods: An observational study in the sleep clinic and the community. Children with characteristics of ADHD, both stimulant-medicated (
n=53), and non-medicated (
n=34), together with control children (
n=53) completed a sleep habits questionnaire prior to undergoing full overnight polysomnographic assessment.
Results: Medicated and non-medicated ADHD subjects were reported to have more sleep disturbances compared with controls. Both groups of ADHD children also demonstrated decreased REM sleep percentage compared with controls (
P=0.006 for ADHDmed;
P=0.02 for ADHDnon). However, the use of stimulant medication (
n=53) was not associated with differences in subjective sleep quality or objective sleep measures, compared to ADHD children not taking any medication (
n=34;
P=n.s.).
Conclusions: Despite the high prevalence of reported sleep disturbance in children with ADHD, stimulant medication appears to have minimal effects on subjective and objective sleep characteristics in children with reported ADHD.</description><identifier>ISSN: 1389-9457</identifier><identifier>EISSN: 1878-5506</identifier><identifier>DOI: 10.1016/S1389-9457(03)00071-6</identifier><identifier>PMID: 14592303</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Attention Deficit Disorder with Hyperactivity - drug therapy ; Attention Deficit Disorder with Hyperactivity - physiopathology ; Attention deficit/hyperactivity disorder ; Case-Control Studies ; Central Nervous System Stimulants - therapeutic use ; Child ; Child, Preschool ; Female ; Health Surveys ; Humans ; Male ; Parents ; Polysomnography ; Rapid eye movement sleep ; Sleep ; Sleep - drug effects ; Sleep, REM ; Stimulant medication</subject><ispartof>Sleep medicine, 2003-07, Vol.4 (4), p.309-316</ispartof><rights>2003</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c361t-6966e5746761b6122bd185b6dd10da8ebf516279e716b31ea0ebd83bafb682823</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/14592303$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>O'Brien, Louise M</creatorcontrib><creatorcontrib>Ivanenko, Anna</creatorcontrib><creatorcontrib>Crabtree, Valerie McLaughlin</creatorcontrib><creatorcontrib>Holbrook, Cheryl R</creatorcontrib><creatorcontrib>Bruner, Jennifer L</creatorcontrib><creatorcontrib>Klaus, Carrie J</creatorcontrib><creatorcontrib>Gozal, David</creatorcontrib><title>The effect of stimulants on sleep characteristics in children with attention deficit/hyperactivity disorder</title><title>Sleep medicine</title><addtitle>Sleep Med</addtitle><description>Objective: To investigate the effects of stimulant medications on subjective and objective sleep characteristics of children with attention deficit/hyperactivity disorder (ADHD) compared with control children.
Methods: An observational study in the sleep clinic and the community. Children with characteristics of ADHD, both stimulant-medicated (
n=53), and non-medicated (
n=34), together with control children (
n=53) completed a sleep habits questionnaire prior to undergoing full overnight polysomnographic assessment.
Results: Medicated and non-medicated ADHD subjects were reported to have more sleep disturbances compared with controls. Both groups of ADHD children also demonstrated decreased REM sleep percentage compared with controls (
P=0.006 for ADHDmed;
P=0.02 for ADHDnon). However, the use of stimulant medication (
n=53) was not associated with differences in subjective sleep quality or objective sleep measures, compared to ADHD children not taking any medication (
n=34;
P=n.s.).
Conclusions: Despite the high prevalence of reported sleep disturbance in children with ADHD, stimulant medication appears to have minimal effects on subjective and objective sleep characteristics in children with reported ADHD.</description><subject>Attention Deficit Disorder with Hyperactivity - drug therapy</subject><subject>Attention Deficit Disorder with Hyperactivity - physiopathology</subject><subject>Attention deficit/hyperactivity disorder</subject><subject>Case-Control Studies</subject><subject>Central Nervous System Stimulants - therapeutic use</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Female</subject><subject>Health Surveys</subject><subject>Humans</subject><subject>Male</subject><subject>Parents</subject><subject>Polysomnography</subject><subject>Rapid eye movement sleep</subject><subject>Sleep</subject><subject>Sleep - drug effects</subject><subject>Sleep, REM</subject><subject>Stimulant medication</subject><issn>1389-9457</issn><issn>1878-5506</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2003</creationdate><recordtype>article</recordtype><recordid>eNqFkE1v1DAQhi1ERT_gJ4B8QvQQ6okT2zmhqmoBqRIHytnyx0Q7kE0W21u0_77e7iKOnDzyPO-M5mHsLYiPIEBdfQdphmboev1ByEshhIZGvWBnYLRp-l6ol7X-i5yy85x_CgEaTPeKnULXD60U8oz9elghx3HEUPgy8lxovZ3cXDJfZp4nxA0PK5dcKJiodkPmNNcvmmLCmf-hsuKuFJwL1UDEkQKVq9Vug_sMPVLZ8Uh5SRHTa3Yyuinjm-N7wX7c3T7cfGnuv33-enN93wSpoDRqUAp73SmtwCtoWx_B9F7FCCI6g37sQbV6QA3KS0An0EcjvRu9Mq1p5QV7f5i7ScvvLeZi15QDTvUuXLbZapCt7PQe7A9gSEvOCUe7SbR2aWdB2L1l-2zZ7hVaIe2zZatq7t1xwdavMf5LHbVW4NMBwHrmI2GyORDOASOlatrGhf6z4gnxQo56</recordid><startdate>20030701</startdate><enddate>20030701</enddate><creator>O'Brien, Louise M</creator><creator>Ivanenko, Anna</creator><creator>Crabtree, Valerie McLaughlin</creator><creator>Holbrook, Cheryl R</creator><creator>Bruner, Jennifer L</creator><creator>Klaus, Carrie J</creator><creator>Gozal, David</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20030701</creationdate><title>The effect of stimulants on sleep characteristics in children with attention deficit/hyperactivity disorder</title><author>O'Brien, Louise M ; Ivanenko, Anna ; Crabtree, Valerie McLaughlin ; Holbrook, Cheryl R ; Bruner, Jennifer L ; Klaus, Carrie J ; Gozal, David</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c361t-6966e5746761b6122bd185b6dd10da8ebf516279e716b31ea0ebd83bafb682823</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2003</creationdate><topic>Attention Deficit Disorder with Hyperactivity - drug therapy</topic><topic>Attention Deficit Disorder with Hyperactivity - physiopathology</topic><topic>Attention deficit/hyperactivity disorder</topic><topic>Case-Control Studies</topic><topic>Central Nervous System Stimulants - therapeutic use</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Female</topic><topic>Health Surveys</topic><topic>Humans</topic><topic>Male</topic><topic>Parents</topic><topic>Polysomnography</topic><topic>Rapid eye movement sleep</topic><topic>Sleep</topic><topic>Sleep - drug effects</topic><topic>Sleep, REM</topic><topic>Stimulant medication</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>O'Brien, Louise M</creatorcontrib><creatorcontrib>Ivanenko, Anna</creatorcontrib><creatorcontrib>Crabtree, Valerie McLaughlin</creatorcontrib><creatorcontrib>Holbrook, Cheryl R</creatorcontrib><creatorcontrib>Bruner, Jennifer L</creatorcontrib><creatorcontrib>Klaus, Carrie J</creatorcontrib><creatorcontrib>Gozal, David</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Sleep medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>O'Brien, Louise M</au><au>Ivanenko, Anna</au><au>Crabtree, Valerie McLaughlin</au><au>Holbrook, Cheryl R</au><au>Bruner, Jennifer L</au><au>Klaus, Carrie J</au><au>Gozal, David</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The effect of stimulants on sleep characteristics in children with attention deficit/hyperactivity disorder</atitle><jtitle>Sleep medicine</jtitle><addtitle>Sleep Med</addtitle><date>2003-07-01</date><risdate>2003</risdate><volume>4</volume><issue>4</issue><spage>309</spage><epage>316</epage><pages>309-316</pages><issn>1389-9457</issn><eissn>1878-5506</eissn><abstract>Objective: To investigate the effects of stimulant medications on subjective and objective sleep characteristics of children with attention deficit/hyperactivity disorder (ADHD) compared with control children.
Methods: An observational study in the sleep clinic and the community. Children with characteristics of ADHD, both stimulant-medicated (
n=53), and non-medicated (
n=34), together with control children (
n=53) completed a sleep habits questionnaire prior to undergoing full overnight polysomnographic assessment.
Results: Medicated and non-medicated ADHD subjects were reported to have more sleep disturbances compared with controls. Both groups of ADHD children also demonstrated decreased REM sleep percentage compared with controls (
P=0.006 for ADHDmed;
P=0.02 for ADHDnon). However, the use of stimulant medication (
n=53) was not associated with differences in subjective sleep quality or objective sleep measures, compared to ADHD children not taking any medication (
n=34;
P=n.s.).
Conclusions: Despite the high prevalence of reported sleep disturbance in children with ADHD, stimulant medication appears to have minimal effects on subjective and objective sleep characteristics in children with reported ADHD.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>14592303</pmid><doi>10.1016/S1389-9457(03)00071-6</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1389-9457 |
| ispartof | Sleep medicine, 2003-07, Vol.4 (4), p.309-316 |
| issn | 1389-9457 1878-5506 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_71323472 |
| source | Elsevier |
| subjects | Attention Deficit Disorder with Hyperactivity - drug therapy Attention Deficit Disorder with Hyperactivity - physiopathology Attention deficit/hyperactivity disorder Case-Control Studies Central Nervous System Stimulants - therapeutic use Child Child, Preschool Female Health Surveys Humans Male Parents Polysomnography Rapid eye movement sleep Sleep Sleep - drug effects Sleep, REM Stimulant medication |
| title | The effect of stimulants on sleep characteristics in children with attention deficit/hyperactivity disorder |
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