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Antifungal Effects Of Endodontic Medicaments
ABSTRACT The eradication of root canal infection is paramount in endodontic treatment. Because fungi are involved in some types of root canal infections, the purpose of this study was to investigate the antifungal effects of several medicaments against the following selected fungal species: Candida...
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| Published in: | Australian endodontic journal 2001-12, Vol.27 (3), p.112-114 |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c3891-4d9e94e8356282d36eda0dc1e52a6f4b5a61b258fd9c95e21252359aa0bb15263 |
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| cites | cdi_FETCH-LOGICAL-c3891-4d9e94e8356282d36eda0dc1e52a6f4b5a61b258fd9c95e21252359aa0bb15263 |
| container_end_page | 114 |
| container_issue | 3 |
| container_start_page | 112 |
| container_title | Australian endodontic journal |
| container_volume | 27 |
| creator | Siqueira Jr, José F. Rĉças, Isabela N. Magalhäes, Fernando A. C. De Uzeda, Milton |
| description | ABSTRACT
The eradication of root canal infection is paramount in endodontic treatment. Because fungi are involved in some types of root canal infections, the purpose of this study was to investigate the antifungal effects of several medicaments against the following selected fungal species: Candida albicans, Candida glabrata, Candida guilliermondii, Candida parapsilosis, and Saccharomyces cerevisiae. The agar diffusion test was the method used. Calcium sulphate or zinc oxide in glycerin showed no inhibitory effects towards any selected fungal species. The pastes of calcium sulphate or calcium hydroxide in camphorated paramonochlorophenol (CPMC)/glycerin showed the most pronounced antifungal effects. Calcium hydroxide in glycerin or chlorhexidine, and chlorhexidine in a detergent also showed antifungal activity, which was, however, much lower than the pastes of calcium sulphate or calcium hydroxide in CPMC/glycerin. Strategies using medicaments that have antifungal effects may assist in the successful management of persistent or secondary endodontic infections caused by fungi. |
| doi_str_mv | 10.1111/j.1747-4477.2001.tb00471.x |
| format | article |
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The eradication of root canal infection is paramount in endodontic treatment. Because fungi are involved in some types of root canal infections, the purpose of this study was to investigate the antifungal effects of several medicaments against the following selected fungal species: Candida albicans, Candida glabrata, Candida guilliermondii, Candida parapsilosis, and Saccharomyces cerevisiae. The agar diffusion test was the method used. Calcium sulphate or zinc oxide in glycerin showed no inhibitory effects towards any selected fungal species. The pastes of calcium sulphate or calcium hydroxide in camphorated paramonochlorophenol (CPMC)/glycerin showed the most pronounced antifungal effects. Calcium hydroxide in glycerin or chlorhexidine, and chlorhexidine in a detergent also showed antifungal activity, which was, however, much lower than the pastes of calcium sulphate or calcium hydroxide in CPMC/glycerin. Strategies using medicaments that have antifungal effects may assist in the successful management of persistent or secondary endodontic infections caused by fungi.</description><identifier>ISSN: 1329-1947</identifier><identifier>EISSN: 1747-4477</identifier><identifier>DOI: 10.1111/j.1747-4477.2001.tb00471.x</identifier><identifier>PMID: 12360664</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Anti-Infective Agents, Local - pharmacology ; Antifungal Agents - pharmacology ; Calcium Hydroxide - pharmacology ; Calcium Sulfate - pharmacology ; Candida - drug effects ; Chlorhexidine - analogs & derivatives ; Chlorhexidine - pharmacology ; Dental Pulp Diseases - drug therapy ; Dental Pulp Diseases - microbiology ; Dentistry ; Humans ; Microbial Sensitivity Tests ; Mycoses - drug therapy ; Root Canal Irrigants - pharmacology ; Saccharomyces cerevisiae - drug effects ; Zinc Oxide - pharmacology</subject><ispartof>Australian endodontic journal, 2001-12, Vol.27 (3), p.112-114</ispartof><rights>2001 Australian Society of Endodontology Inc</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3891-4d9e94e8356282d36eda0dc1e52a6f4b5a61b258fd9c95e21252359aa0bb15263</citedby><cites>FETCH-LOGICAL-c3891-4d9e94e8356282d36eda0dc1e52a6f4b5a61b258fd9c95e21252359aa0bb15263</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12360664$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Siqueira Jr, José F.</creatorcontrib><creatorcontrib>Rĉças, Isabela N.</creatorcontrib><creatorcontrib>Magalhäes, Fernando A. C.</creatorcontrib><creatorcontrib>De Uzeda, Milton</creatorcontrib><title>Antifungal Effects Of Endodontic Medicaments</title><title>Australian endodontic journal</title><addtitle>Aust Endod J</addtitle><description>ABSTRACT
The eradication of root canal infection is paramount in endodontic treatment. Because fungi are involved in some types of root canal infections, the purpose of this study was to investigate the antifungal effects of several medicaments against the following selected fungal species: Candida albicans, Candida glabrata, Candida guilliermondii, Candida parapsilosis, and Saccharomyces cerevisiae. The agar diffusion test was the method used. Calcium sulphate or zinc oxide in glycerin showed no inhibitory effects towards any selected fungal species. The pastes of calcium sulphate or calcium hydroxide in camphorated paramonochlorophenol (CPMC)/glycerin showed the most pronounced antifungal effects. Calcium hydroxide in glycerin or chlorhexidine, and chlorhexidine in a detergent also showed antifungal activity, which was, however, much lower than the pastes of calcium sulphate or calcium hydroxide in CPMC/glycerin. Strategies using medicaments that have antifungal effects may assist in the successful management of persistent or secondary endodontic infections caused by fungi.</description><subject>Anti-Infective Agents, Local - pharmacology</subject><subject>Antifungal Agents - pharmacology</subject><subject>Calcium Hydroxide - pharmacology</subject><subject>Calcium Sulfate - pharmacology</subject><subject>Candida - drug effects</subject><subject>Chlorhexidine - analogs & derivatives</subject><subject>Chlorhexidine - pharmacology</subject><subject>Dental Pulp Diseases - drug therapy</subject><subject>Dental Pulp Diseases - microbiology</subject><subject>Dentistry</subject><subject>Humans</subject><subject>Microbial Sensitivity Tests</subject><subject>Mycoses - drug therapy</subject><subject>Root Canal Irrigants - pharmacology</subject><subject>Saccharomyces cerevisiae - drug effects</subject><subject>Zinc Oxide - pharmacology</subject><issn>1329-1947</issn><issn>1747-4477</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><recordid>eNqVkE1Lw0AQhhdRbK3-BQkePJm435t4EEpJq1Lbi-Jx2WQ3kpqPmk2x_fduSKhn5zID886z7APADYIBcnW_CZCgwqdUiABDiII2gZAKFOxPwPi4OnUzwZGPIipG4MLaDYSYEoHOwQhhwiHndAzuplWbZ7vqUxVenGUmba23zry40rWu3Sr1Xo3OU1WaqrWX4CxThTVXQ5-A93n8Nnvyl-vF82y69FMSRsinOjIRNSFhHIdYE260gjpFhmHFM5owxVGCWZjpKI2YwQgzTFikFEwSxDAnE3Dbc7dN_b0ztpVlblNTFKoy9c5K4T7GBApd8KEPpk1tbWMyuW3yUjUHiaDsXMmN7ITITojsXMnBldy74-vhlV1SGv13Oshxgcc-8JMX5vAPtJzGL25wAL8H5LY1-yNANV-SCyKY_Fgt5JwvVlwwJBfkF3rUhmc</recordid><startdate>200112</startdate><enddate>200112</enddate><creator>Siqueira Jr, José F.</creator><creator>Rĉças, Isabela N.</creator><creator>Magalhäes, Fernando A. 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C. ; De Uzeda, Milton</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3891-4d9e94e8356282d36eda0dc1e52a6f4b5a61b258fd9c95e21252359aa0bb15263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Anti-Infective Agents, Local - pharmacology</topic><topic>Antifungal Agents - pharmacology</topic><topic>Calcium Hydroxide - pharmacology</topic><topic>Calcium Sulfate - pharmacology</topic><topic>Candida - drug effects</topic><topic>Chlorhexidine - analogs & derivatives</topic><topic>Chlorhexidine - pharmacology</topic><topic>Dental Pulp Diseases - drug therapy</topic><topic>Dental Pulp Diseases - microbiology</topic><topic>Dentistry</topic><topic>Humans</topic><topic>Microbial Sensitivity Tests</topic><topic>Mycoses - drug therapy</topic><topic>Root Canal Irrigants - pharmacology</topic><topic>Saccharomyces cerevisiae - drug effects</topic><topic>Zinc Oxide - pharmacology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Siqueira Jr, José F.</creatorcontrib><creatorcontrib>Rĉças, Isabela N.</creatorcontrib><creatorcontrib>Magalhäes, Fernando A. 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C.</au><au>De Uzeda, Milton</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antifungal Effects Of Endodontic Medicaments</atitle><jtitle>Australian endodontic journal</jtitle><addtitle>Aust Endod J</addtitle><date>2001-12</date><risdate>2001</risdate><volume>27</volume><issue>3</issue><spage>112</spage><epage>114</epage><pages>112-114</pages><issn>1329-1947</issn><eissn>1747-4477</eissn><abstract>ABSTRACT
The eradication of root canal infection is paramount in endodontic treatment. Because fungi are involved in some types of root canal infections, the purpose of this study was to investigate the antifungal effects of several medicaments against the following selected fungal species: Candida albicans, Candida glabrata, Candida guilliermondii, Candida parapsilosis, and Saccharomyces cerevisiae. The agar diffusion test was the method used. Calcium sulphate or zinc oxide in glycerin showed no inhibitory effects towards any selected fungal species. The pastes of calcium sulphate or calcium hydroxide in camphorated paramonochlorophenol (CPMC)/glycerin showed the most pronounced antifungal effects. Calcium hydroxide in glycerin or chlorhexidine, and chlorhexidine in a detergent also showed antifungal activity, which was, however, much lower than the pastes of calcium sulphate or calcium hydroxide in CPMC/glycerin. Strategies using medicaments that have antifungal effects may assist in the successful management of persistent or secondary endodontic infections caused by fungi.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>12360664</pmid><doi>10.1111/j.1747-4477.2001.tb00471.x</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1329-1947 |
| ispartof | Australian endodontic journal, 2001-12, Vol.27 (3), p.112-114 |
| issn | 1329-1947 1747-4477 |
| language | eng |
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| source | Wiley-Blackwell Read & Publish Collection |
| subjects | Anti-Infective Agents, Local - pharmacology Antifungal Agents - pharmacology Calcium Hydroxide - pharmacology Calcium Sulfate - pharmacology Candida - drug effects Chlorhexidine - analogs & derivatives Chlorhexidine - pharmacology Dental Pulp Diseases - drug therapy Dental Pulp Diseases - microbiology Dentistry Humans Microbial Sensitivity Tests Mycoses - drug therapy Root Canal Irrigants - pharmacology Saccharomyces cerevisiae - drug effects Zinc Oxide - pharmacology |
| title | Antifungal Effects Of Endodontic Medicaments |
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