Neurobiology and neuropathology underlie the neuropsychological deficits associated with traumatic brain injury

The neurobiological and neuropathological bases that underlie the neuropsychological deficits associated with traumatic brain injury (TBI), including mild TBI, are further reviewed. The article provides an update on neuroimaging methods and findings in the study of TBI since the author’s published a...

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Bibliographic Details
Published in:Archives of clinical neuropsychology 2003-08, Vol.18 (6), p.595-621
Main Author: Bigler, Erin D
Format: Article
Language:English
Subjects:
Biological and medical sciences
Brain Injuries - complications
Humans
Injuries of the nervous system and the skull. Diseases due to physical agents
Medical sciences
Mental Disorders - etiology
Mental Disorders - pathology
Mental Disorders - psychology
Neurobiology
Neuropathology
Severity of Illness Index
Traumas. Diseases due to physical agents
Traumatic brain injury
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Summary:The neurobiological and neuropathological bases that underlie the neuropsychological deficits associated with traumatic brain injury (TBI), including mild TBI, are further reviewed. The article provides an update on neuroimaging methods and findings in the study of TBI since the author’s published address of the 1999 Distinguished Neuropsychologist Award of the National Academy of Neuropsychology (see Bigler, 2001a). The review addresses and answers criticisms raised about the interface of neuroimaging abnormalities and neuropsychological deficits, particularly in mild TBI. The article provides further guidelines in making the link between neuroimaging findings and neuropsychological outcome in the clinical practice of neuropsychology. The article also opines on the future role and importance that neuroimaging will play in neuropsychological practice, particularly functional neuroimaging methods.
ISSN:0887-6177
1873-5843
DOI:10.1016/S0887-6177(02)00156-7