Anatomy and functionality of leptomeningeal anastomoses: A review

This review seeks to provide a structured presentation of existing knowledge of leptomeningeal anastomoses from anatomic and functional points of view and to identify problems and possible research directions to foster a better understanding of the subject and of stroke mechanisms. Available data sh...

Full description

Saved in:
Bibliographic Details
Published in:Stroke (1970) 2003-11, Vol.34 (11), p.2750-2762
Main Authors: BROZICI, Mariana, VAN DER ZWAN, Albert, HILLEN, Berend
Format: Article
Language:English
Subjects:
Animals
Arteriovenous Anastomosis - anatomy & histology
Arteriovenous Anastomosis - physiology
Biological and medical sciences
Hemodynamics - physiology
Humans
Medical sciences
Meninges - anatomy & histology
Meninges - blood supply
Meninges - physiology
Models, Animal
Neurology
Stroke - prevention & control
Vascular diseases and vascular malformations of the nervous system
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This review seeks to provide a structured presentation of existing knowledge of leptomeningeal anastomoses from anatomic and functional points of view and to identify problems and possible research directions to foster a better understanding of the subject and of stroke mechanisms. Available data show that leptomeningeal anastomoses may be important in understanding stroke mechanisms and that leptomeningeal anastomoses play an important role in penumbra outcome. However, the literature shows no consensus between statements on the existence of leptomeningeal anastomoses and compensatory capacity. By analyzing the available literature and identifying the factors that contribute to this confusion, we found that variability and the functional consequences thereof are important but that quantitative data are lacking. Moreover, vascular remodeling is an issue to consider.
ISSN:0039-2499
1524-4628
DOI:10.1161/01.STR.0000095791.85737.65