Effect of muscle oxygenation during resistance exercise on anabolic hormone response

• Published in: Medicine and science in sports and exercise 2003-11, Vol.35 (11), p.1929-1934
• Main Authors: HOFFMAN, Jay R, JOOHEE IM, RUNDELL, Kenneth W, JIE KANG, NIOKA, Shoko, SPEIRING, Barry A, KIME, Ryoto, CHANCE, Britton
• Format: Article
• Language: English
• Subjects: Adult; Biological and medical sciences; Exercise - physiology; Fundamental and applied biological sciences. Psychology; Growth Hormone - blood; Humans; Male; Muscle, Skeletal - metabolism; Oxygen - metabolism; Physical Education and Training; Space life sciences; Striated muscle. Tendons; Testosterone - blood; Vertebrates: osteoarticular system, musculoskeletal system; Weight Lifting
• ISSN: 0195-9131; 1530-0315
• DOI: 10.1249/01.mss.0000093613.30362.df

The mechanisms that underlie the affect of acute program variables on muscle growth and strength development for strength/power athletes have been of great interest. This investigation examined the affects of two different resistance exercise protocols on muscle oxygenation, and the anabolic hormonal response to such exercise. Eleven experienced resistance-trained male athletes performed four sets of the squat exercise using either a low-intensity, high-volume (LI; 15 repetitions at 60% one-repetition maximum [1-RM]) or high-intensity, low-volume (HI; 4 repetitions at 90% 1-RM) load. Venous blood samples were obtained before (Pre), immediate (IP), 20- (20P), and 40-min (40P) postexercise. Continuous-wave near-infrared spectroscopy was used to measure oxygen desaturation during exercise. No differences in muscle deoxygenation were seen between LI and HI. However, time-dependent postexercise reoxygenation was significantly different between the two exercise sessions (35.3 +/- 17.4 s vs 24.5 +/- 14.3 s in LI and HI, respectively). Testosterone and growth hormone (GH) concentrations were significantly elevated from Pre at IP, 20P, and 40P in both LI and HI. GH concentrations were higher (P