Association of glaucoma with neurodegenerative diseases with apoptotic cell death: Alzheimer’s disease and Parkinson’s disease

PURPOSE: To report a possible association of glaucoma with Parkinson’s disease and Alzheimer’s disease. METHODS: Retrospective chart review (observational case series). The ophthalmologic charts of 49 patients with Alzheimer’s disease and of 38 patients with Parkinson’s disease were reviewed to dete...

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Bibliographic Details
Published in:American journal of ophthalmology 2002, Vol.133 (1), p.135-137
Main Authors: Bayer, Andreas U, Keller, Othmar N, Ferrari, Francis, Maag, Klaus-Peter
Format: Article
Language:English
Subjects:
Aged
Alzheimer Disease - complications
Alzheimer Disease - diagnosis
Apoptosis
Biological and medical sciences
Female
Glaucoma and intraocular pressure
Glaucoma, Open-Angle - complications
Glaucoma, Open-Angle - diagnosis
Humans
Intraocular Pressure
Male
Medical sciences
Ophthalmology
Optic Disk - pathology
Parkinson Disease - complications
Parkinson Disease - diagnosis
Prevalence
Retrospective Studies
Risk Factors
Vision Disorders - complications
Visual Fields
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Summary:PURPOSE: To report a possible association of glaucoma with Parkinson’s disease and Alzheimer’s disease. METHODS: Retrospective chart review (observational case series). The ophthalmologic charts of 49 patients with Alzheimer’s disease and of 38 patients with Parkinson’s disease were reviewed to determine the occurrence rate of glaucoma among these patients. RESULTS: Glaucomatous visual field defects or cup-to-disk ratios of 0.8 or greater were recorded in 12 patients with Alzheimer’s disease (24.5%) and in 9 patients with Parkinson’s disease (23.7%). CONCLUSION: Patients with Alzheimer’s disease and Parkinson’s disease may have an increased occurrence rate of glaucoma.
ISSN:0002-9394
1879-1891
DOI:10.1016/S0002-9394(01)01196-5