Basaloid squamous cell carcinoma of the oral mucosa: a new case and review of 45 cases in the literature

• Published in: Oral oncology 2002, Vol.38 (1), p.120-124
• Main Authors: Ide, F., Shimoyama, T., Horie, N., Kusama, K.
• Format: Article
• Language: English
• Subjects: Aged; Basaloid squamous cell carcinoma; Biological and medical sciences; Carcinoma, Basosquamous - pathology; Diagnosis, Differential; Differential diagnosis; Head and neck; Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics; Humans; Male; Medical sciences; Mouth Neoplasms - pathology; Neoplasm Staging; Oral mucosa; Otorhinolaryngology. Stomatology; Prognosis; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the upper aerodigestive tract; Tumors; Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
• ISSN: 1368-8375; 1879-0593
• DOI: 10.1016/S1368-8375(01)00032-X

Basaloid squamous cell carcinoma (BSCC) of the oral mucosa other than the tongue is uncommon. We report a case of a 67-year-old man who diagnosed with Stage I BSCC in the floor of the mouth. This early stage presentation carries a considerably better prognosis. Clinical summary of 46 cases of oral BSCC indicated that the tongue base was the most preferred site (61%). The patients were 19 males and 15 females with the mean age of 61 years ( n=34). Most presented with Stage III or IV disease (62%). Even at the initial presentation, 47% had cervical lymph node metastases. Its aggressive clinical behaviour was characterized by a high incidence of local recurrence (32%), regional lymph node metastases (52%), and mortality rate (38%). Because of the advanced stage at presentation, oral BSCC is prognostically worse.