Long-term benzimidazole treatment of alveolar echinococcosis with hematogenic subcutaneous and bone dissemination

We report a case of advanced alveolar echinococcosis (AE) that presented like a malignant tumor. It was diagnosed histologically from a subcutaneous nodule with skin inflammation on the right leg. Additionally, the patient showed bone metastases in the lower thoracic spine and the left third toe. Th...

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Bibliographic Details
Published in:Medical microbiology and immunology 2003-11, Vol.192 (4), p.193-195
Main Authors: SCHEURING, Urban J, SEITZ, Hanns Martin, WELLMANN, Axel, HARTLAPP, Joachim H, TAPPE, Dennis, BREHM, Klaus, SPENGLER, Ulrich, SAUERBRUCH, Tilmann, ROCKSTROH, Jürgen K
Format: Article
Language:English
Subjects:
Albendazole - pharmacology
Albendazole - therapeutic use
Anticestodal Agents - pharmacology
Anticestodal Agents - therapeutic use
benzimidazole
Benzimidazoles - pharmacology
Benzimidazoles - therapeutic use
Biological and medical sciences
Bone Diseases, Infectious - drug therapy
Bone Diseases, Infectious - parasitology
Bone Diseases, Infectious - pathology
Case studies
Diagnosis, Differential
Disease Progression
Diseases caused by cestodes
Drug therapy
Echinococcoses
echinococcosis
Echinococcosis, Hepatic - diagnosis
Echinococcosis, Hepatic - drug therapy
Echinococcosis, Hepatic - pathology
Female
Fundamental and applied biological sciences. Psychology
Helminthic diseases
Humans
Infectious diseases
Mebendazole - pharmacology
Mebendazole - therapeutic use
Medical diagnosis
Medical sciences
Medical treatment
Microbiology
Middle Aged
Neoplasms - diagnosis
Parasitemia - drug therapy
Parasitic diseases
Skin Diseases, Infectious - drug therapy
Skin Diseases, Infectious - parasitology
Skin Diseases, Infectious - pathology
Tumors
Citations: Items that cite this one
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Description
Summary:We report a case of advanced alveolar echinococcosis (AE) that presented like a malignant tumor. It was diagnosed histologically from a subcutaneous nodule with skin inflammation on the right leg. Additionally, the patient showed bone metastases in the lower thoracic spine and the left third toe. This is the first case with proven hematogenic spread of AE to a subcutaneous site. The patient was treated with albendazole and remained stable for 6 years. When progression of AE occurred the therapy was changed to mebendazole, resulting in a stable condition for further 4 years.
ISSN:0300-8584
1432-1831
DOI:10.1007/s00430-002-0171-9