Electroencephalography Findings in Adult Patients with West Nile Virus—Associated Meningitis and Meningoencephalitis

Eighteen adult patients with serologically confirmed West Nile virus (WNV)–associated meningitis or meningoencephalitis were admitted to our hospital during the 2000 West Nile fever outbreak in Israel. Thirteen of the patients had a more severe and prolonged clinical course, and an electroencephalog...

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Bibliographic Details
Published in:Clinical infectious diseases 2003-12, Vol.37 (11), p.1573-1578
Main Authors: Gandelman-Marton, R., Kimiagar, I., Itzhaki, A., Klein, C., Theitler, J., Rabey, J. M.
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Brief Reports
Diagnosis, Differential
Disease Outbreaks
Electroencephalography
Encephalitis
Female
Fever
Headache
Humans
Infections
Infectious diseases
Male
Medical sciences
Meningitis, Viral - diagnosis
Meningitis, Viral - physiopathology
Meningitis, Viral - virology
Meningoencephalitis
Meningoencephalitis - diagnosis
Meningoencephalitis - physiopathology
Meningoencephalitis - virology
Middle Aged
Sleep stages
Viral meningitis
Viruses
West Nile fever
West Nile Fever - epidemiology
West Nile Fever - physiopathology
West Nile virus
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Summary:Eighteen adult patients with serologically confirmed West Nile virus (WNV)–associated meningitis or meningoencephalitis were admitted to our hospital during the 2000 West Nile fever outbreak in Israel. Thirteen of the patients had a more severe and prolonged clinical course, and an electroencephalogram (EEG) was, therefore, requested. A specific EEG pattern was seen in 8 patients, consisting of generalized slowing, which was more prominent over the anterior regions. Generalized slowing that was prominent over the temporal area was seen in 2 patients, and intermittent slowing over the temporal region was seen in 1 patient. Two patients had normal EEG findings. We suggest that WNV meningoencephalitis should be considered in the differential diagnosis of meningitis or meningoencephalitis with a prolonged clinical course and anteriorly predominant slowing on an EEG.
ISSN:1058-4838
1537-6591
DOI:10.1086/379516