Acinar arterial changes with chronic lung disease of prematurity in the surfactant era

Because echocardiographic studies on infants with chronic lung disease (CLD) suggest that pulmonary hypertension (PH) may contribute to its severity, we studied acinar arterial walls in the following surfactant‐era infants: controls (n = 38): 22–41 weeks of gestational age (GA), exposed briefly to o...

Full description

Saved in:
Bibliographic Details
Published in:Pediatric pulmonology 2003-12, Vol.36 (6), p.482-489
Main Authors: Thibeault, Donald W., Truog, William E., Ekekezie, Ikechukwu I.
Format: Article
Language:English
Subjects:
Actins - analysis
arterial changes
Arteries - pathology
Biological and medical sciences
Bronchopulmonary Dysplasia - drug therapy
Bronchopulmonary Dysplasia - pathology
Chronic Disease
chronic lung disease
Endothelium, Vascular - pathology
Female
Humans
Infant, Newborn
Infant, Postmature
Infant, Premature, Diseases - drug therapy
Infant, Premature, Diseases - pathology
Lung - blood supply
Lung - pathology
Lung Diseases - drug therapy
Lung Diseases - pathology
Medical sciences
Muscle, Smooth, Vascular - pathology
Organ Size
Persistent Fetal Circulation Syndrome - pathology
Pneumology
Pulmonary Surfactants - therapeutic use
Respiration, Artificial
Respiratory system : syndromes and miscellaneous diseases
surfactant
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Because echocardiographic studies on infants with chronic lung disease (CLD) suggest that pulmonary hypertension (PH) may contribute to its severity, we studied acinar arterial walls in the following surfactant‐era infants: controls (n = 38): 22–41 weeks of gestational age (GA), exposed briefly to oxygen and positive pressure ventilation, died within 48 hr of birth; prolonged rupture of fetal membranes (PROM) and persistent pulmonary hypertension (PPHN) (n = 17); and SCORE (integrated area under curve of average daily FiO2 × average daily MAP) groups (
ISSN:8755-6863
1099-0496
DOI:10.1002/ppul.10349