Successful treatment of Staphylococcus aureus bacterial endocarditis in a renal transplant recipient

: We report the successful treatment of Staphylococcus aureus endocarditis in a renal transplant recipient with preservation of his renal allograft. A 44‐year‐old man presented to the emergency room with sudden onset of fevers and rigors 7 weeks after renal transplantation. Infective endocarditis wa...

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Bibliographic Details
Published in:Transplant infectious disease 2003-09, Vol.5 (3), p.144-146
Main Authors: D'Cunha, P.T., Davenport, D.S., Fisher, K.A.
Format: Article
Language:English
Subjects:
Adult
Anti-Bacterial Agents - administration & dosage
Anti-Bacterial Agents - therapeutic use
Bacterial diseases
Biological and medical sciences
Cardiology. Vascular system
Endocardial and cardiac valvular diseases
endocarditis
Endocarditis, Bacterial - drug therapy
Endocarditis, Bacterial - microbiology
Heart
Human bacterial diseases
Humans
Infectious diseases
Injections, Intravenous
kidney transplantation
Kidney Transplantation - adverse effects
Male
Medical sciences
Staphylococcal Infections - drug therapy
Staphylococcal Infections - microbiology
Staphylococcal infections, streptococcal infections, pneumococcal infections
Staphylococcus aureus
Staphylococcus aureus - drug effects
Treatment Outcome
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Summary:: We report the successful treatment of Staphylococcus aureus endocarditis in a renal transplant recipient with preservation of his renal allograft. A 44‐year‐old man presented to the emergency room with sudden onset of fevers and rigors 7 weeks after renal transplantation. Infective endocarditis was diagnosed by Duke's Criteria (Durack et al. New criteria for the diagnosis of infective endocarditis. Am J Med 1994: 96: 200–209) with multiple positive blood cultures for S. aureus and a mitral valve vegetation on transesophageal echocardiogram. He was treated with intravenous antibiotics for 6 weeks with continuation of his immunosuppression. He has remained clinically stable for over 5 years. Although the treatment of S. aureus endocarditis in immunosuppressed transplant patients has traditionally resulted in loss of their allograft, prompt diagnosis and appropriate antibiotics with continued immunosuppressive therapy resulted in a successful outcome and allograft preservation in this case.
ISSN:1398-2273
1399-3062
DOI:10.1034/j.1399-3062.2003.00015.x