Predictors of death in infants hospitalized with pertussis: a case-control study of 16 pertussis deaths in Canada

To describe the clinical course of fatal cases of pertussis and identify predictors of death at the time of presentation for medical care. Case-control study of 16 deaths from pertussis identified by the Immunization Monitoring Program, Active (IMPACT) surveillance network (January 1991-December 200...

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Bibliographic Details
Published in:The Journal of pediatrics 2003-11, Vol.143 (5), p.576-581
Main Authors: Mikelova, Lynda K, Halperin, Scott A, Scheifele, David, Smith, Bruce, Ford-Jones, Elizabeth, Vaudry, Wendy, Jadavji, Taj, Law, Barbara, Moore, Dorothy
Format: Article
Language:English
Subjects:
Breast Feeding - statistics & numerical data
Canada - epidemiology
Case-Control Studies
Female
Hospital Mortality
Hospitalization
Humans
Infant
Infant, Newborn
Male
Pertussis Vaccine - administration & dosage
Prospective Studies
Survival Rate
Vaccination - statistics & numerical data
Whooping Cough - mortality
Whooping Cough - prevention & control
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Summary:To describe the clinical course of fatal cases of pertussis and identify predictors of death at the time of presentation for medical care. Case-control study of 16 deaths from pertussis identified by the Immunization Monitoring Program, Active (IMPACT) surveillance network (January 1991-December 2001) matched with 32 nonfatal cases by age, date, and geography. Differences were compared by Fisher exact test and logistic regression. A multivariate model was developed using stepwise logistic regression. All 16 fatal cases were ≤6 months old; 13 were
ISSN:0022-3476
1097-6833
DOI:10.1067/S0022-3476(03)00365-2