The investigation of an equilibrium dependent reaction for the formation of enamines in a microchemical system

The paper describes the equilibrium dependant reaction for the formation of enamines in a microchemical system utilising electroosmotic flow (EOF) for fluid mobilisation. The authors have shown that the reaction can be carried out without the presence of a Lewis acid catalyst, in addition the enamin...

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Bibliographic Details
Published in:Lab on a chip 2001-09, Vol.1 (1), p.64-65
Main Authors: Sands, M, Haswell, S J, Kelly, S M, Skelton, V, Morgan, D O, Styring, P, Warrington, B
Format: Article
Language:English
Online Access:Get full text
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Summary:The paper describes the equilibrium dependant reaction for the formation of enamines in a microchemical system utilising electroosmotic flow (EOF) for fluid mobilisation. The authors have shown that the reaction can be carried out without the presence of a Lewis acid catalyst, in addition the enamine intermediate was synthesised at room temperature using mild solvent conditions. A 42% conversion of cyclohexanone into the enamine has been achieved to date.
ISSN:1473-0197
DOI:10.1039/b104036g