The prevalence of nocturia and its effect on health‐related quality of life and sleep in a community sample in the USA

OBJECTIVE To evaluate the prevalence of nocturia and its effects, with and without concomitant overactive bladder (OAB, i.e. urgency, frequency, urge incontinence and nocturia), on health‐related quality of life (HRQoL) and sleep. SUBJECTS AND METHODS A national survey was conducted in the USA to as...

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Bibliographic Details
Published in:BJU international 2003-12, Vol.92 (9), p.948-954
Main Authors: Coyne, K.S., Zhou, Z., Bhattacharyya, S.K., Thompson, C.L., Dhawan, R., Versi, E.
Format: Article
Language:English
Subjects:
Age Distribution
Analysis. Health state
Biological and medical sciences
Cross-Sectional Studies
Epidemiology
Female
General aspects
Health Surveys
Humans
Male
Medical sciences
Middle Aged
nocturia
overactive bladder
Prevalence
Public health. Hygiene
Public health. Hygiene-occupational medicine
Quality of Life
United States - epidemiology
Urination Disorders - epidemiology
Urination Disorders - psychology
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Summary:OBJECTIVE To evaluate the prevalence of nocturia and its effects, with and without concomitant overactive bladder (OAB, i.e. urgency, frequency, urge incontinence and nocturia), on health‐related quality of life (HRQoL) and sleep. SUBJECTS AND METHODS A national survey was conducted in the USA to assess the prevalence of OAB and nocturia. A nested case‐control study was conducted among respondents with OAB symptoms and age‐ and gender‐matched controls, with participants completing a series of questionnaires on HRQoL (OAB‐q, Short Form‐36, and Medical Outcomes Study (MOS) sleep scale). Descriptive analyses, t‐tests, analysis of variance with post hoc comparisons and multivariate regressions were used to analyse the data. RESULTS In all, 5204 people participated in the survey, with 919 in the nested case‐control study. The sample population had a mean age of 45.8 years, was 52.6% female and 80% Caucasian. In the community sample, 31% reported > 1 void/night and 14.2% reported > 2 voids/night. The prevalence of nocturia increased with age, with no gender differences. For OAB cases, 66.8% reported > 1 void/night and 42.2% reported > 2. In the case‐control cohort there were significant HRQoL differences (P 
ISSN:1464-4096
1464-410X
DOI:10.1111/j.1464-410X.2003.04527.x