Wound healing effects of Heliotropium indicum, Plumbago zeylanicum and Acalypha indica in rats

The ethanolic extracts of Heliotropium indicum, Plumbago zeylanicum and Acalypha indica were evaluated for their wound healing activity in rats. Wound healing activity was studied using excision and incision wound models in rats following topical application. Animals were divided into four groups wi...

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Bibliographic Details
Published in:Journal of ethnopharmacology 2002-02, Vol.79 (2), p.249-251
Main Authors: SURESH REDDY, J, RAJESWARA RAO, P, REDDY, Mada S
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Drug Evaluation, Preclinical - methods
Drug Evaluation, Preclinical - statistics & numerical data
Euphorbiaceae - chemistry
Female
General pharmacology
Heliotropium - chemistry
Male
Medical sciences
Models, Biological
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Phytotherapy - methods
Phytotherapy - statistics & numerical data
Plant Extracts - pharmacology
Plant Extracts - therapeutic use
Plumbaginaceae - chemistry
Rats
Rats, Inbred Lew
Suture Techniques
Wound Healing - drug effects
Wound Healing - physiology
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Summary:The ethanolic extracts of Heliotropium indicum, Plumbago zeylanicum and Acalypha indica were evaluated for their wound healing activity in rats. Wound healing activity was studied using excision and incision wound models in rats following topical application. Animals were divided into four groups with six in each group. Ten percent w/v extract of each plant was prepared in saline for topical application. H. indicum possesses better wound healing activity than P. zeylanicum and A. indica. Tensile strength results indicate better activity of H. indicum on remodeling phase of wound healing.
ISSN:0378-8741
1872-7573
DOI:10.1016/S0378-8741(01)00388-9