High-performance liquid chromatography/mass spectrometry analysis of botanical medicines and dietary supplements: a review

This article reviews research on the qualitative and quantitative analysis by high-performance column liquid chromatography/mass spectrometry (LC/MS) and LC/tandem mass spectrometry (LC/MS/MS) of botanical drugs, drug substances or preparations, and finished botanical products. In addition, LC/MS an...

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Bibliographic Details
Published in:Journal of AOAC International 2003-09, Vol.86 (5), p.873-881
Main Author: Sherma, J
Format: Article
Language:English
Subjects:
Biological and medical sciences
chemical analysis
Chromatography, High Pressure Liquid - instrumentation
Chromatography, High Pressure Liquid - methods
dietary supplements
Dietary Supplements - analysis
Food industries
Fundamental and applied biological sciences. Psychology
General aspects
herbal medicines
high performance liquid chromatography
liquid chromatography
mass spectrometry
Mass Spectrometry - instrumentation
Mass Spectrometry - methods
medicinal plants
Methods of analysis, processing and quality control, regulation, standards
Plant Preparations - analysis
Spectrometry, Mass, Electrospray Ionization
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Summary:This article reviews research on the qualitative and quantitative analysis by high-performance column liquid chromatography/mass spectrometry (LC/MS) and LC/tandem mass spectrometry (LC/MS/MS) of botanical drugs, drug substances or preparations, and finished botanical products. In addition, LC/MS and LC/MS/MS techniques and commercial instruments are described and compared briefly, and prospects for future use of these methods for the analysis of botanicals are suggested. Some applications of direct MS without LC are also described.
ISSN:1060-3271
1944-7922
DOI:10.1093/jaoac/86.5.873