Microbial Pathogenesis: New Niches for Salmonella

Salmonella occupies a vacuolar compartment inside cells of its host. Recent studies have shown that the fate of this vacuole is different in various cell types, and that the outcome of colonization is determined by both the infecting bacterium and defense mechanisms of the host cell.

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Bibliographic Details
Published in:Current biology 2002-01, Vol.12 (1), p.R15-R17
Main Authors: Brumell, J.H, Perrin, A.J, Goosney, D.L, Finlay, B.B
Format: Article
Language:English
Subjects:
Animals
DNA Replication
DNA, Bacterial - genetics
Endocytosis
Epithelial Cells - microbiology
Host-Parasite Interactions
Humans
Mice
Salmonella
Salmonella Infections - microbiology
Salmonella typhimurium - growth & development
Salmonella typhimurium - metabolism
Salmonella typhimurium - pathogenicity
Vacuoles - microbiology
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Description
Summary:Salmonella occupies a vacuolar compartment inside cells of its host. Recent studies have shown that the fate of this vacuole is different in various cell types, and that the outcome of colonization is determined by both the infecting bacterium and defense mechanisms of the host cell.
ISSN:0960-9822
1879-0445
DOI:10.1016/S0960-9822(01)00640-6