Hepatic haemodynamics: interrelationships between contrast enhancement and perfusion on CT and Doppler perfusion indices

This study compares three techniques that evaluate hepatic haemodynamics for the detection of metastatic liver disease to determine the interrelationships between the techniques and to assess their equivalence. The three techniques studied were dedicated CT measurements of hepatic enhancement, CT me...

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Bibliographic Details
Published in:British journal of radiology 2002, Vol.75 (889), p.17-23
Main Authors: FUENTES, M. A, KEITH, C. J, GRIFFITHS, M, DURBRIDGE, G, MILES, K. A
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Breast Neoplasms - diagnostic imaging
Colonic Neoplasms - diagnostic imaging
Digestive system
Digestive system. Abdomen
Female
Humans
Image Enhancement
Investigative techniques, diagnostic techniques (general aspects)
Liver - blood supply
Liver - diagnostic imaging
Liver Neoplasms - blood supply
Liver Neoplasms - diagnostic imaging
Liver Neoplasms - secondary
Male
Medical sciences
Middle Aged
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Regional Blood Flow
Tomography, X-Ray Computed - methods
Tropical medicine
Ultrasonic investigative techniques
Ultrasonography, Doppler, Color
Ultrasonography, Doppler, Duplex
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Summary:This study compares three techniques that evaluate hepatic haemodynamics for the detection of metastatic liver disease to determine the interrelationships between the techniques and to assess their equivalence. The three techniques studied were dedicated CT measurements of hepatic enhancement, CT measurements of perfusion and Doppler perfusion indices. 53 patients with proven malignancies of either breast or colon underwent a single location dynamic CT for measurement of hepatic perfusion and enhancement, whilst a subset of 12 patients underwent both CT perfusion and Doppler perfusion studies. Statistically significant correlations were found between CT arterial phase enhancement and CT arterial perfusion (r=0.612, p
ISSN:0007-1285
1748-880X
DOI:10.1259/bjr.75.889.750017