Hip section modulus, a measure of bending resistance, is more strongly related to reported physical activity than BMD

We hypothesized that measures of physical activity would have a closer relationship with section modulus (SM), an indicator of bending resistance, than with bone mineral density (BMD) because physical activity might expand the bony envelope, which tends to reduce BMD for a constant bone mineral cont...

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Bibliographic Details
Published in:Osteoporosis international 2003-11, Vol.14 (11), p.941-949
Main Authors: KAPTOGE, S, DALZELL, N, JAKES, R. W, WAREHAM, N, DAY, N. E, KHAW, K. T, BECK, T. J, LOVERIDGE, N, REEVE, J
Format: Article
Language:English
Subjects:
Absorptiometry, Photon
Age
Aged
Aging - physiology
Biological and medical sciences
Bone density
Bone Density - physiology
Bones
Cohort analysis
Diseases of the osteoarticular system
Elasticity
Exercise
Female
Femur - physiology
Femur Neck - physiology
Follow-Up Studies
Fractures
Humans
Lifestyles
Male
Medical sciences
Motor Activity - physiology
Osteoporosis
Osteoporosis. Osteomalacia. Paget disease
Prospective Studies
Stress, Mechanical
Weight-Bearing - physiology
Womens health
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Summary:We hypothesized that measures of physical activity would have a closer relationship with section modulus (SM), an indicator of bending resistance, than with bone mineral density (BMD) because physical activity might expand the bony envelope, which tends to reduce BMD for a constant bone mineral content. Four hundred twenty-three men and 436 women (mean age 72 years, SD =3) were recruited from a prospective population-based cohort study to a study of hip bone loss. Hip BMD was measured on two occasions 2-5 years apart (mean 2.7, DXA-Hologic 1,000 W). Hip structural analysis (HSA) software was used to calculate SM and BMD from the DXA scans on three narrow regions: the narrow neck (NN), intertrochanter (IT) and shaft (S). A physical activity and lifestyle questionnaire was administered at baseline. Multivariate repeated measures analysis of variance was used to model the associations between personal attributes (weight, height, age), physical activity and lifestyle variables with SM, cross-sectional area (CSA), sub-periosteal diameter (PD) and BMD. Men and women were analysed together after tests for interactions with gender, which were found not to be significant. In all regions female gender was associated with having lower values of all outcomes, and body weight was positively associated with all outcomes, i.e., SM, CSA, PD and BMD ( P
ISSN:0937-941X
1433-2965
DOI:10.1007/s00198-003-1484-2