Pleomorphic Liposarcoma Metastatic to the Thyroid Gland

Although carcinoma is rarely metastatic to the thyroid gland, it has an established place in the differential diagnosis of cold nodules on radionuclide thyroid scans in patients with known cancers. A case of metastatic pleomorphic liposarcoma with involvement of the thyroid gland adds to the list of...

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Bibliographic Details
Published in:Clinical nuclear medicine 2002-01, Vol.27 (1), p.9-10
Main Authors: BASHIR, HUMAYUN, KHALID NAWAZ, M, SHAH, MAZHAR A, AHMAD, EJAZ
Format: Article
Language:English
Subjects:
Biological and medical sciences
Biopsy
Bone Neoplasms - secondary
Endocrinopathies
Female
Follow-Up Studies
Humans
Liposarcoma - diagnostic imaging
Liposarcoma - pathology
Liposarcoma - secondary
Liposarcoma - therapy
Malignant tumors
Medical sciences
Middle Aged
Radionuclide Imaging
Sodium Pertechnetate Tc 99m
Soft Tissue Neoplasms - pathology
Thigh
Thyroid Neoplasms - diagnostic imaging
Thyroid Neoplasms - pathology
Thyroid Neoplasms - secondary
Thyroid Neoplasms - therapy
Thyroid. Thyroid axis (diseases)
Tropical medicine
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Summary:Although carcinoma is rarely metastatic to the thyroid gland, it has an established place in the differential diagnosis of cold nodules on radionuclide thyroid scans in patients with known cancers. A case of metastatic pleomorphic liposarcoma with involvement of the thyroid gland adds to the list of cases of metastases to the thyroid gland. A patient with known metastatic pleomorphic liposarcoma with a palpable thyroid nodule of 2 months’ duration had a thyroid scan with 130 MBq (3.5 mCi) Tc-99m pertechnetate. The scan showed a cold nodule occupying most of the right lobe of the thyroid. Cytologic analysis of a fine-needle aspirate from this cold nodule confirmed metastasis from the known primary cancer, pleomorphic liposarcoma. In a patient with a known primary tumor, a nodule in the thyroid gland should be considered a metastatic lesion, regardless of the time since the primary tumor was diagnosed and treated, until proved otherwise.
ISSN:0363-9762
1536-0229
DOI:10.1097/00003072-200201000-00002