Three-dimensional Color Doppler Sonography and Uterine Artery Arteriography of Fibroids: Assessment of Changes in Vascularity Before and After Embolization

• Published in: Journal of ultrasound in medicine 2002-02, Vol.21 (2), p.129-133
• Main Authors: Muniz, C. Joseph, Fleischer, Arthur C, Donnelly, Edwin F, Mazer, Murray J
• Format: Article
• Language: English
• Subjects: Adult; Angiography; Biological and medical sciences; Collateral Circulation; Embolization, Therapeutic; Female; Female genital diseases; Genital system. Mammary gland; Gynecology. Andrology. Obstetrics; Humans; Imaging, Three-Dimensional; Investigative techniques, diagnostic techniques (general aspects); Leiomyoma - blood supply; Leiomyoma - diagnostic imaging; Leiomyoma - therapy; Medical sciences; Retrospective Studies; Tumors; Ultrasonic investigative techniques; Ultrasonography, Doppler, Color; Uterine Neoplasms - blood supply; Uterine Neoplasms - diagnostic imaging; Uterine Neoplasms - therapy; Uterus - blood supply
• ISSN: 0278-4297; 1550-9613
• DOI: 10.7863/jum.2002.21.2.129

To assess the accuracy of three-dimensional color Doppler sonography and uterine artery arteriography in depicting changes in fibroid vascularity before and after embolization. Preembolization and postembolization three-dimensional color Doppler sonography and selective uterine artery arteriography were retrospectively compared in 15 patients who underwent uterine artery embolization for treatment of symptomatic fibroids. Three-dimensional color Doppler sonography was performed by using a scanner with color power angiographic imaging capability. Vascularity was quantified by using an estimation of power-weighted pixel density as described by our group in previously published studies. Uterine artery arteriography was performed by using a standard selective microcatheter embolization technique. For purposes of comparison, fibroids were classified as either hypervascular or hypovascular relative to myometrial vascularity before and minutes to several hours after uterine artery embolization. Changes in fibroid vascularity (i.e., from hypervascular to hypovascular) as depicted by three-dimensional color Doppler sonography were compared with those shown on uterine artery arteriography and classified as being in agreement or disagreement. In 13 (87%) of 15 patients there was agreement; in 2 (13%) of 15 there was disagreement. In both cases of disagreement, three-dimensional color Doppler sonography showed collateral flow not depicted by uterine artery arteriography The mean reduction in quantitated vascularity after uterine artery embolization was 44% (range, 19%-78%). Three-dimensional color Doppler sonography accurately depicts fibroid vascularity and in some cases can reveal collateral flow not depicted by uterine artery arteriography.