Study of total lipid peroxidation and antioxidant activity in pulmonary and mediastinal malignant and benign tumor tissue

Total lipid peroxidation and antioxidant activity were studied in pulmonary and mediastinal malignant and benign neoplasms. In malignant tumors total lipid peroxidation increased and antioxidant activity decreased; the intensity of these shifts depended on histological characteristics and degree of...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2003-09, Vol.136 (3), p.283-285
Main Authors: Korotkina, R N, Spiridonova, O V, Matskevich, G N, Kucheinik, A Sh, Kunitsyn, A G, Vishnevskii, A A, Karelin, A A
Format: Article
Language:English
Subjects:
Adenocarcinoma - pathology
Aged
Antioxidants - metabolism
Antioxidants - pharmacology
Bronchial Neoplasms - pathology
Cell Line, Tumor
Female
Glutathione Peroxidase - metabolism
Humans
Lipid Metabolism
Lipid Peroxidation
Lipid Peroxides - metabolism
Male
Middle Aged
Neoplasms - metabolism
Neoplasms - pathology
Pulmonary Alveoli - pathology
Thymoma - pathology
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Summary:Total lipid peroxidation and antioxidant activity were studied in pulmonary and mediastinal malignant and benign neoplasms. In malignant tumors total lipid peroxidation increased and antioxidant activity decreased; the intensity of these shifts depended on histological characteristics and degree of malignancy: the most pronounced changes were observed in thymoma and adenocarcinoma tissues and minimum changes were found in bronchoalveolar carcinoma tissue.
ISSN:0007-4888
1573-8221
DOI:10.1023/B:BEBM.0000008984.82726.2e