Screening of antibiotic resistant inhibitors from local plant materials against two different strains of Staphylococcus aureus

The inhibitory effects of methanolic extracts of 19 Jordanian plants and their combinations with seven antibiotics, on the resistance of Staphylococcus aureus were checked. Methicillin resistant S. aureus (MRSA), which was isolated from patient and a standard strain of S. aureus were used. Our resul...

Full description

Saved in:
Bibliographic Details
Published in:Journal of ethnopharmacology 2002-03, Vol.79 (3), p.359-364
Main Authors: DARWISH, Rula M, ABURJAI, T, AL-KHALIL, S, MAHAFZAH, A
Format: Article
Language:English
Subjects:
Anti-Bacterial Agents
Biological and medical sciences
Drug Evaluation, Preclinical - methods
Drug Evaluation, Preclinical - statistics & numerical data
Drug Resistance, Bacterial - physiology
Drug Therapy, Combination - pharmacology
General pharmacology
Humans
Medical sciences
Methicillin Resistance
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Plant Extracts - pharmacology
Plant Structures
Staphylococcus aureus - drug effects
Staphylococcus aureus - growth & development
Staphylococcus aureus - isolation & purification
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The inhibitory effects of methanolic extracts of 19 Jordanian plants and their combinations with seven antibiotics, on the resistance of Staphylococcus aureus were checked. Methicillin resistant S. aureus (MRSA), which was isolated from patient and a standard strain of S. aureus were used. Our results showed that there are variations in the effect of some combinations used on the resistant and the standard strains probably due to structural changes. Common results between the two strains showed that combinations of gentamicin and chloramphenicol could be improved by the use of plant materials, whereas nalidixic acid activity cannot be improved when combined with plant materials.
ISSN:0378-8741
DOI:10.1016/S0378-8741(01)00411-1