The Role of Technetium-99m MAG3 Renal Imaging in the Diagnosis of Acute Tubular Necrosis of Native Kidneys

The differential diagnosis for patients with acute renal failure of their native kidneys, as a result of primary intrarenal disease, includes acute tubular necrosis, glomerulonephritis, and interstitial nephritis. The role of MAG3 renography has not been studied in this setting. The authors describe...

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Bibliographic Details
Published in:Clinical nuclear medicine 2002-03, Vol.27 (3), p.165-168
Main Authors: BLAUSTEIN, DANIEL A, MYINT, MAUNG M, BABU, KRISHNAN, AVRAM, MORRELL M, CHANDRAMOULI, BELUR S
Format: Article
Language:English
Subjects:
Acute Kidney Injury - diagnostic imaging
Acute Kidney Injury - etiology
Aged
Biological and medical sciences
Diagnosis, Differential
Glomerulonephritis - diagnostic imaging
Humans
Investigative techniques, diagnostic techniques (general aspects)
Kidney - diagnostic imaging
Kidney Tubular Necrosis, Acute - complications
Kidney Tubular Necrosis, Acute - diagnostic imaging
Male
Medical sciences
Middle Aged
Nephritis, Interstitial - diagnostic imaging
Nephrology. Urinary tract diseases
Nephropathies. Renovascular diseases. Renal failure
Radionuclide Imaging
Radionuclide investigations
Radiopharmaceuticals
Technetium Tc 99m Mertiatide
Tubulopathies
Urinary system
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Summary:The differential diagnosis for patients with acute renal failure of their native kidneys, as a result of primary intrarenal disease, includes acute tubular necrosis, glomerulonephritis, and interstitial nephritis. The role of MAG3 renography has not been studied in this setting. The authors describe four patients with acute renal failure in whom MAG3 renal imaging reliably identified acute tubular necrosis, as confirmed by follow-up kidney biopsies. In contrast to the poor parenchymal uptake observed in glomerulonephritis and interstitial nephritis, MAG3 shows a distinctive pattern in patients with acute tubular necrosis. For patients with acute renal failure, a renal scan can facilitate decision-making regarding the initiation of therapy.
ISSN:0363-9762
1536-0229
DOI:10.1097/00003072-200203000-00002