Crystallization and synchrotron X-ray diffraction studies of human interleukin-22

Human interleukin‐22, a novel member of the cytokine family, has been crystallized in hanging drops using the vapour‐diffusion technique. Preliminary X‐ray diffraction experiments using synchrotron radiation reveal that the protein crystallizes in space group P212121, with unit‐cell parameters a = 5...

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Bibliographic Details
Published in:Acta crystallographica. Section D, Biological crystallography. Biological crystallography., 2002-03, Vol.58 (3), p.529-530
Main Authors: Nagem, R. A. P., Lucchesi, K. W., Colau, D., Dumoutier, L., Renauld, J.-C., Polikarpov, I.
Format: Article
Language:English
Subjects:
Crystallization
Crystallography, X-Ray
Humans
IFN-γ
IL-10
IL-22
IL-TIF
interleukin
Interleukin-22
Interleukins - chemistry
Protein Conformation
Recombinant Proteins - chemistry
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Summary:Human interleukin‐22, a novel member of the cytokine family, has been crystallized in hanging drops using the vapour‐diffusion technique. Preliminary X‐ray diffraction experiments using synchrotron radiation reveal that the protein crystallizes in space group P212121, with unit‐cell parameters a = 55.44, b = 61.62, c = 73.43 Å, and diffracts beyond 2.00 Å resolution.
ISSN:1399-0047
0907-4449
1399-0047
DOI:10.1107/S0907444902001063