CRETINISM IN A NORTH AMERICAN BLACK BEAR(URSUS AMERICANUS)

Congenital hyperplastic goiter and cretinism were documented in a 16 month‐old male North American black bear (Ursus americanus). The cub was captured at approximately 8 months of age and maintained for an additional 8 months in captivity. Clinical signs included growth retardation, clumsiness, and...

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Bibliographic Details
Published in:Veterinary radiology & ultrasound 2002-01, Vol.43 (1), p.31-36
Main Authors: Duncan JR, Robert B., Jones, Jeryl C., David Moll, H., Moon, Martha M., Blodgett, Dennis J., Vaughan, Michael R.
Format: Article
Language:English
Subjects:
abnormalities
Animals
bears
congenital hypothyroidism
Congenital Hypothyroidism - diagnostic imaging
Congenital Hypothyroidism - pathology
Congenital Hypothyroidism - veterinary
cretinism
goiter
Hypothyroidism - diagnostic imaging
Hypothyroidism - veterinary
Male
thyroid gland hyperplasia
Tomography, X-Ray Computed
Ursidae
wild
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Summary:Congenital hyperplastic goiter and cretinism were documented in a 16 month‐old male North American black bear (Ursus americanus). The cub was captured at approximately 8 months of age and maintained for an additional 8 months in captivity. Clinical signs included growth retardation, clumsiness, and facial dysmorphism. Hypothyroidism was documented by determining serum triiodothyronine (T3) and thyroxine (T4) levels. Lysosomal storage disease was ruled out by measuring various lysosomal enzyme activities. Serologic, radiographic, computed tomographic, necropsy, and histopathologic findings were consistent with congenital hypothyroidism and cretinism.
ISSN:1058-8183
1740-8261
DOI:10.1111/j.1740-8261.2002.tb00439.x