Isoflavone content of the soy based supplements

A large number of soy isoflavone products with indications of possible health effects are available on the market. Fifteen different soy based products were analyzed using high performance liquid chromatography (HPLC) with coulometric electrode array detector to determine the total amount of isoflav...

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Bibliographic Details
Published in:Journal of pharmaceutical and biomedical analysis 2002-04, Vol.28 (1), p.1-11
Main Authors: Nurmi, T, Mazur, W, Heinonen, S, Kokkonen, J, Adlercreutz, H
Format: Article
Language:English
Subjects:
Analysis
Biological and medical sciences
Chromatography, High Pressure Liquid - methods
Chromatography, High Pressure Liquid - statistics & numerical data
Coulometric detection
Dietary Supplements - analysis
Drug Evaluation
General pharmacology
Glycine max - chemistry
Isoflavones
Isoflavones - analysis
Medical sciences
Pharmacology. Drug treatments
Soy product
Supplement
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Summary:A large number of soy isoflavone products with indications of possible health effects are available on the market. Fifteen different soy based products were analyzed using high performance liquid chromatography (HPLC) with coulometric electrode array detector to determine the total amount of isoflavones in aglycones after the hydrolysis and identify the different forms of the isoflavone conjugates. The aim of the study was to evaluate how well the isoflavone content data supplied by the producers correspond to our analysis results. Only one product contained isoflavones measured in aglycones the same amount as was the value given by the producer. The total amount of the isoflavones in aglycones ranged from 0.121 to 201 mg/g. Measured amounts of isoflavones in aglycones after the hydrolysis were in general lower than the values in the product labels. Product data were often confusing and the concrete amount of isoflavones was difficult to find out.
ISSN:0731-7085
1873-264X
DOI:10.1016/S0731-7085(01)00612-4