Prognostic significance of an elevated creatine kinase in the absence of an elevated troponin I during an acute coronary syndrome

In patients with troponin-negative acute coronary syndromes, creatine kinase (CK)-MB elevation predicts a significantly higher risk of death and major acute cardiac events compared with CK-MB negative patients. This risk is accentuated in troponin-negative, CK-MB positive patients who do not demonst...

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Bibliographic Details
Published in:The American journal of cardiology 2003-12, Vol.92 (12), p.1442-1444
Main Authors: Yee, Kimberly C., Mukherjee, Debabrata, Smith, Dean E., Kline-Rogers, Eva M., Fang, Jianming, Mehta, Rajendra H., Almanaseer, Yassar, Akhras, Eyad, Cooper, Jeanna V., Eagle, Kim A.
Format: Article
Language:English
Subjects:
Acute Disease
Aged
Biological and medical sciences
Biomarkers - blood
Cardiology. Vascular system
Cardiovascular disease
Coronary Disease - blood
Coronary Disease - complications
Coronary Disease - mortality
Coronary heart disease
Creatine Kinase - blood
Female
Heart
Heart Failure - complications
Humans
Isoenzymes - blood
Logistic Models
Male
Medical research
Medical sciences
Middle Aged
Multivariate Analysis
Patient Readmission - statistics & numerical data
Predictive Value of Tests
Prognosis
Syndrome
Troponin I - blood
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Summary:In patients with troponin-negative acute coronary syndromes, creatine kinase (CK)-MB elevation predicts a significantly higher risk of death and major acute cardiac events compared with CK-MB negative patients. This risk is accentuated in troponin-negative, CK-MB positive patients who do not demonstrate ST elevation by electrocardiogram.
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2003.08.055