Recollection memory deficits in patients with major depressive disorder predicted by past depressions but not current mood state or treatment status

Background. Neuropsychological studies have suggested that memory systems reliant on medial temporal lobe structures are impaired in patients with depression. There is less data regarding whether this impairment is specific to recollection memory systems, and whether clinical features predict impair...

Full description

Saved in:
Bibliographic Details
Published in:Psychological medicine 2002-02, Vol.32 (2), p.251-258
Main Authors: MacQUEEN, G. M., GALWAY, T. M., HAY, J., YOUNG, L. T., JOFFE, R. T.
Format: Article
Language:English
Subjects:
Adult
Adult and adolescent clinical studies
Affect - physiology
Antidepressants
Antidepressive Agents - therapeutic use
Biological and medical sciences
Canada
Deficits
Depression
Depressive Disorder, Major - diagnosis
Depressive Disorder, Major - drug therapy
Depressive Disorder, Major - physiopathology
Depressive Disorder, Major - psychology
Emotional disorders
Female
Humans
Illnesses
Male
Medical sciences
Memory
Mental depression
Mental Recall - physiology
Middle Aged
Mood disorders
Neuropsychological Tests
Neuropsychology
Original Article
Paired-Associate Learning - physiology
Patients
Predictors
Prior
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychosis
Questionnaires
Recurrence
Retention (Psychology) - physiology
Temporal Lobe - physiopathology
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background. Neuropsychological studies have suggested that memory systems reliant on medial temporal lobe structures are impaired in patients with depression. There is less data regarding whether this impairment is specific to recollection memory systems, and whether clinical features predict impairment. This study sought to address these issues. Method. A computerized process-dissociation memory task was utilized to dissociate recollection and habit memory in 40 patients with past or current major depression and 40 age, sex and IQ matched non-psychiatric control subjects. The Cognitive Failures Questionnaire was used to assess patients’ perceptions of day-to-day memory failures. Results. Patients had impaired recollection memory (t = 4·7, P
ISSN:0033-2917
1469-8978
DOI:10.1017/S0033291701004834