Time‐courses in renin and blood pressure during sleep in humans

We previously described a strong concordance between nocturnal oscillations in plasma renin activity (PRA) and the rapid eye movement (REM) and non‐REM (NREM) sleep cycles, but the mechanisms inducing PRA oscillations remain to be identified. This study was designed to examine whether they are linke...

Full description

Saved in:
Bibliographic Details
Published in:Journal of sleep research 2002-03, Vol.11 (1), p.73-79
Main Authors: CHARLOUX, A., PIQUARD, F., EHRHART, J., METTAUER, B., GENY, B., SIMON, C., BRANDENBERGER, G.
Format: Article
Language:English
Subjects:
Adult
autonomic nervous system
Autonomic Nervous System - metabolism
blood pressure
Blood Pressure - physiology
Circadian Rhythm - physiology
Electroencephalography
Female
Heart Rate - physiology
Humans
Male
renin
Renin - blood
sleep
Sleep, REM - physiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We previously described a strong concordance between nocturnal oscillations in plasma renin activity (PRA) and the rapid eye movement (REM) and non‐REM (NREM) sleep cycles, but the mechanisms inducing PRA oscillations remain to be identified. This study was designed to examine whether they are linked to sleep stage‐related changes in arterial blood pressure (ABP). Analysis of sleep electroencephalographic (EEG) activity in the delta frequency band, intra‐arterial pressure, and PRA measured every 10 min was performed in eight healthy subjects. Simultaneously, the ratio of low frequency power to low frequency power + high frequency power [LF/(LF + HF)] was calculated using spectral analysis of R–R intervals. The cascade of physiological events that led to increased renin release during NREM sleep could be characterized. First, the LF/(LF + HF) ratio significantly (P 
ISSN:0962-1105
1365-2869
DOI:10.1046/j.1365-2869.2002.00277.x