Iron deficiency anemia as the only sign of infection with Helicobacter pylori: A report of 9 pediatric cases

Recently, an association between Helicobacter pylori (HP) and iron deficiency anemia (IDA) was proposed. We describe 9 pediatric patients with a history of long-standing IDA and HP infection. After HP test results were confirmed to be positive, anti-HP therapy consisting of omeprazole, clarithromyci...

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Bibliographic Details
Published in:International journal of hematology 2003-12, Vol.78 (5), p.429-431
Main Authors: RUSSO-MANCUSO, Giovanna, BRANCIFORTE, Francesca, LICCIARDELLO, Maria, LA SPINA, Milena
Format: Article
Language:English
Subjects:
Adolescent
Anemia, Hypochromic - blood
Anemia, Hypochromic - etiology
Anemias. Hemoglobinopathies
Biological and medical sciences
Biomarkers
Child
Child, Preschool
Diseases of red blood cells
Female
Helicobacter Infections - complications
Helicobacter Infections - diagnosis
Helicobacter Infections - drug therapy
Helicobacter pylori - isolation & purification
Hematologic and hematopoietic diseases
Humans
Iron - deficiency
Iron - therapeutic use
Male
Medical sciences
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Summary:Recently, an association between Helicobacter pylori (HP) and iron deficiency anemia (IDA) was proposed. We describe 9 pediatric patients with a history of long-standing IDA and HP infection. After HP test results were confirmed to be positive, anti-HP therapy consisting of omeprazole, clarithromycin, and amoxicillin was administered for 2 weeks. The hematologic profile and iron status were assessed before and periodically after the end of the eradication regimen. The eradication of HP was associated with stable normalization of iron stores. HP infection may be involved in cases of IDA of unknown origin, and the eradication of HP is associated with the resolution of anemia.
ISSN:0925-5710
1865-3774
DOI:10.1007/BF02983815