Near-Total Laryngectomy in Advanced Laryngeal and Pyriform Cancers

• Published in: The Laryngoscope 2002-02, Vol.112 (2), p.375-380
• Main Authors: Pradhan, Sultan A., D'Cruz, Anil K., Pai, Prathamesh S., Mohiyuddin, Azeem
• Format: Article
• Language: English
• Subjects: Adult; Age Distribution; Aged; Biological and medical sciences; cancer; Disease-Free Survival; Female; Follow-Up Studies; Glottis - pathology; Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics; Humans; Laryngeal Neoplasms - mortality; Laryngeal Neoplasms - pathology; Laryngeal Neoplasms - surgery; Laryngectomy - adverse effects; Laryngectomy - methods; Laryngectomy - rehabilitation; Laryngoscopy - methods; larynx; Male; Medical sciences; Middle Aged; Near-total laryngectomy; Neoplasm Staging; Otorhinolaryngology. Stomatology; pyriform; Sex Distribution; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the upper aerodigestive tract; Survival Rate; Treatment Outcome; Tumors; Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
• ISSN: 0023-852X; 1531-4995
• DOI: 10.1097/00005537-200202000-00031

Objective To demonstrate the oncologic and physiological safety of near‐total laryngectomy (NTL), its success in voice conservation, and its versatility for use in extensive resections that necessitate pharyngoplasty, and even in post‐radiation recurrences. Study In this study of 137 cases of NTL for cancer of the larynx (45 cases) and pyriform (92 cases), 86.9% were stage T3/T4 and 60.6% were N+. A total of 8.8% had extended pharyngeal resections necessitating patch pharyngoplasty (ENTLP). In 10.9% cases, NTL was used as salvage of post‐radiation failures. Concurrent neck dissection was performed in 99 cases. Results A total of 70.1% was alive and disease‐free at the last follow‐up ranging from 12 months to 104 months (median, 35 mo). A total of 7.3% had local/locoregional recurrences and 11.7% had purely regional recurrences. The local control rate for post‐radiation salvage with NTL was 93.3%. A total of 88.6% developed communicable speech, and the speech success rate was 100% in 12 cases of ENTLP. Complications included major wound dehiscence with total shunt breakdown in 2 cases (1.5%), pharyngeal leak requiring surgical intervention in 7 cases (3.6%), significant aspiration through the shunt necessitating completion laryngectomy in 1 case (0.7%), and complete shunt stenosis in 9 cases (6.6%). Conclusion The study shows that NTL is an oncologically safe voice conservation procedure in advanced, lateralized laryngeal and pyriform cancers treated not only per primum, but also in carefully selected post‐radiation failures. It has a high success rate of speech development even in those cases requiring extensive pharyngeal resections. Major complications were acceptably low.