Risk stratification in diabetic patients with a previous myocardial infarction

We used Kaplan-Meier 2-year survival analysis on CAST registry patients to estimate prognostic power of VPC frequency (≥10/hr), presence of nonsustained ventricular tachycardia (NSVT), left ventricular ejection fraction, and presence of diabetes. We also used meta-analysis of reports in the literatu...

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Bibliographic Details
Published in:Journal of electrocardiology 2003-01, Vol.36, p.121-125
Main Authors: Bailey, James J, Hodges, Morrison, Church, Timothy R
Format: Article
Language:English
Subjects:
Cardiac Complexes, Premature - physiopathology
Diabetes Mellitus - mortality
Electrocardiography
Humans
Myocardial Infarction - complications
Prognosis
Risk Factors
Stroke Volume - physiology
Survival Rate
Tachycardia, Ventricular - physiopathology
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Summary:We used Kaplan-Meier 2-year survival analysis on CAST registry patients to estimate prognostic power of VPC frequency (≥10/hr), presence of nonsustained ventricular tachycardia (NSVT), left ventricular ejection fraction, and presence of diabetes. We also used meta-analysis of reports in the literature to estimate prognostic power of signal-averaged electrocardiogram (SAECG) and electrophysiological tests (EPS) as well as VPCs, NSVT, and LVEF. Combined results from CAST analysis and literature meta-analysis yielded sensitivity and specificity for VPCs, NSVT, SAECG, LVEF, Diabetes, and EPS. The overall 2 year event rate for life-threatening arrhythmias or death was 7.88% for 51,144 cases in the combined CAST and literature data. After segmenting the population 21.3% were diabetic with a predicted 2 yr event rate of 13.5% and 78.7% were nondiabetic event rate of 6.4%. We defined low risk as
ISSN:0022-0736
1532-8430
DOI:10.1016/j.jelectrocard.2003.09.035