Plasma levels of natriuretic peptide and echocardiographic parameters in patients with Duchenne's progressive muscular dystrophy

We investigated the relationship between plasma atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) levels and systolic and diastolic cardiac function, determined by echocardiography, in 63 patients with Duchenne's progressive muscular dystrophy (DMD) (age range 8-21 years). Th...

Full description

Saved in:
Bibliographic Details
Published in:Pediatric cardiology 2002-03, Vol.23 (2), p.160-166
Main Authors: Mori, K, Manabe, T, Nii, M, Hayabuchi, Y, Kuroda, Y, Tatara, K
Format: Article
Language:English
Subjects:
Adolescent
Adult
Atrial Natriuretic Factor - blood
Biomarkers
Child
Diastole
Humans
Male
Muscular Dystrophy, Duchenne - blood
Muscular Dystrophy, Duchenne - complications
Muscular Dystrophy, Duchenne - diagnostic imaging
Natriuretic Peptide, Brain - blood
Sensitivity and Specificity
Systole
Ultrasonography
Ventricular Dysfunction, Left - blood
Ventricular Dysfunction, Left - etiology
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We investigated the relationship between plasma atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) levels and systolic and diastolic cardiac function, determined by echocardiography, in 63 patients with Duchenne's progressive muscular dystrophy (DMD) (age range 8-21 years). The relationship between shortening fraction of the left ventricle and ANP and BNP levels was curvilinear rather than linear: When the shortening fraction was >15%, increases in ANP and BNP levels were minimal. However, if the shortening fraction was
ISSN:0172-0643
1432-1971
DOI:10.1007/s00246-001-0040-0