Left Ventricular Dysfunction in Children with Fulminant Enterovirus 71 Infection: An Evaluation of the Clinical Course

We describe 2 children with typical hand, foot, and mouth disease due to enterovirus 71 infection, 1 of whom died. Both cases were complicated by acute fulminant shock syndrome; the patients had remarkable acute left ventricular dysfunction. The clinical experience indicates that the rapid death ass...

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Bibliographic Details
Published in:Clinical infectious diseases 2002-04, Vol.34 (7), p.1020-1024
Main Authors: Huang, Fang-Liang, Jan, Sheng-Ling, Chen, Po-Yen, Chi, Ching-Shiang, Wang, Teh-Ming, Fu, Yun-Ching, Tsai, Chi-Ren, Chang, Yan
Format: Article
Language:English
Subjects:
Biological and medical sciences
Blood
Blood pressure
Brief Reports
Child, Preschool
Echocardiography
Enterovirus
Enterovirus - pathogenicity
Enterovirus Infections - complications
Enterovirus Infections - mortality
Fatal Outcome
Female
Hand foot and mouth disease
Heart
Heart assist devices
Human viral diseases
Humans
Infant
Infections
Infectious diseases
Male
Medical sciences
Oxygen
Pulmonary edema
Shock, Cardiogenic - etiology
Ventricular Dysfunction, Left - etiology
Ventricular Dysfunction, Left - mortality
Viral cardiopathies
Viral diseases
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Summary:We describe 2 children with typical hand, foot, and mouth disease due to enterovirus 71 infection, 1 of whom died. Both cases were complicated by acute fulminant shock syndrome; the patients had remarkable acute left ventricular dysfunction. The clinical experience indicates that the rapid death associated with fulminant enterovirus rhombencephalitis is the result of rapid cardiogenic shock rather than neurogenic pulmonary edema.
ISSN:1058-4838
1537-6591
DOI:10.1086/339445