Assessment of the Binax NOW Streptococcus pneumoniae Urinary Antigen Test in Children with Nasopharyngeal Pneumococcal Carriage

We evaluated the Binax NOW Streptococcus pneumoniae urinary antigen assay by testing 210 healthy children aged 2-60 months living in urban slums of Quito, Ecuador. Healthy children with nasopharyngeal carriage of S. pneumoniae were significantly more likely to have positive urinary antigen test resu...

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Bibliographic Details
Published in:Clinical infectious diseases 2002-04, Vol.34 (7), p.1025-1028
Main Authors: Davidson H. Hamer, Josefina Egas, Estrella, Bertha, William B. Mac Leod, Griffiths, Jeffrey K., Fernando Sempértegui
Format: Article
Language:English
Subjects:
Antigens
Antigens, Bacterial - urine
Bacterial diseases
Biological and medical sciences
Brief Reports
Carrier State - epidemiology
Carrier State - microbiology
Child growth
Child nutrition
Child nutrition disorders
Child, Preschool
Children
False Positive Reactions
Human bacterial diseases
Humans
Infant
Infants
Infectious diseases
Medical sciences
Nasopharyngeal Diseases - microbiology
Pneumococcal pneumonia
Reagent Kits, Diagnostic
Sensitivity and Specificity
Staphylococcal infections, streptococcal infections, pneumococcal infections
Streptococcus pneumoniae
Streptococcus pneumoniae - isolation & purification
Urine
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Summary:We evaluated the Binax NOW Streptococcus pneumoniae urinary antigen assay by testing 210 healthy children aged 2-60 months living in urban slums of Quito, Ecuador. Healthy children with nasopharyngeal carriage of S. pneumoniae were significantly more likely to have positive urinary antigen test results than were children who were not carriers (30 of 138 vs. 3 of 71 children; chi²=10.8; P
ISSN:1058-4838
1537-6591
DOI:10.1086/339446