Proliferating cell nuclear antigen (PCNA) immunoreactivity and development of the pineal complex and habenula of the sea lamprey

The development of the pineal complex and the habenula of the sea lamprey was studied with proliferating cell nuclear antigen (PCNA) immunocytochemistry. The pineal organ and the habenula primordia appeared in late embryos, and neuron differentiation began in prolarvae, as indicated by the presence...

Full description

Saved in:
Bibliographic Details
Published in:Brain research bulletin 2002-02, Vol.57 (3), p.285-287
Main Authors: Villar-Cheda, Begoña, Pérez-Costas, Emma, Meléndez-Ferro, Miguel, Manoel Abalo, Xesús, Rodrı́guez-Muñoz, Rolando, Anadón, Ramón, Celina Rodicio, Marı́a
Format: Article
Language:English
Subjects:
Agnathans
Animals
Biological and medical sciences
Cell proliferation
Embryo, Nonmammalian - metabolism
Habenula - embryology
Habenula - growth & development
Immunohistochemistry
Lampreys - embryology
Lampreys - growth & development
Lampreys - metabolism
Larva - metabolism
Petromyzon marinus
Photoreceptive organs
Pineal Gland - embryology
Pineal Gland - growth & development
Proliferating Cell Nuclear Antigen - metabolism
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The development of the pineal complex and the habenula of the sea lamprey was studied with proliferating cell nuclear antigen (PCNA) immunocytochemistry. The pineal organ and the habenula primordia appeared in late embryos, and neuron differentiation began in prolarvae, as indicated by the presence of PCNA-negative cells. The parapineal primordium could not be distinguished until early prolarval stages, and cell differentiation was delayed to the larval period. Although the number of cycling (PCNA-immunoreactive) cells gradually decreased during the larval period in the three organs studied, their patterns of differentiation were different. We conclude that the unusual developmental pattern observed is related with the complex life cycle of lampreys.
ISSN:0361-9230
1873-2747
DOI:10.1016/S0361-9230(01)00702-X