A UK Multi-centre Experience with a Second-generation Endovascular Stent-graft: Results from the Zenith Users Group

• Published in: European journal of vascular and endovascular surgery 2004, Vol.27 (1), p.51-55
• Main Authors: Hinchliffe, R.J, Goldberg, J, MacSweeney, S.T.R, On behalf of the Zenith Users Group
• Format: Article
• Language: English
• Subjects: Abdominal aortic aneurysm; Aged; Aortic Aneurysm, Abdominal - surgery; Blood Vessel Prosthesis; Endovascular aneurysm repair; Female; Humans; Male; Prosthesis Design; Stents; Treatment Outcome; Zenith stent-graft
• ISSN: 1078-5884; 1532-2165
• DOI: 10.1016/j.ejvs.2003.10.004

Background. Endovascular aneurysm repair has been criticised for high rates of technical failure and secondary intervention. Second generation stent-grafts have been developed in an attempt to reduce these problems. The results of a UK multi-centre experience with a second generation device (Zenith) are presented. Methods. Data were collected retrospectively from five experienced UK vascular centres in patients undergoing endovascular aneurysm repair with the Zenith stent-graft. Results. A total of 269 patients underwent attempted aneurysm repair with the Zenith device. Median aneurysm diameter was 65 (interquartile range 52–78) mm. There were no conversions to open repair. Peri-operative mortality was 4.1% (11/269). On the initial post-operative scan, 94.1% of aneurysms were successfully excluded. During a median follow-up of 363 (interquartile range 154–720) days there were 19 secondary interventions and two aneurysm ruptures. Conclusions. Second generation endovascular stent-graft designs such as the Zenith are associated with low rates of intra-operative technical complications. Few secondary interventions have been necessary during follow-up; however, surveillance is essential to ensure they continue to perform.