The hepoxilin stable analogue, PBT-3, inhibits primary, platelet-related hemostasis in whole blood measured in vitro with the PFA-100

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Bibliographic Details
Published in:Thrombosis research 2003, Vol.112 (4), p.245-248
Main Authors: Reynaud, Denis, Clark, Dewi, Qiao, Na, Rand, Margaret L, Pace-Asciak, Cecil R
Format: Article
Language:English
Subjects:
8,11,14-Eicosatrienoic Acid - analogs & derivatives
8,11,14-Eicosatrienoic Acid - pharmacology
Adenosine Diphosphate - pharmacology
Biological and medical sciences
Blood Platelets - drug effects
Blood Platelets - physiology
Blood vessels and receptors
Closure time
Collagen - pharmacology
Fundamental and applied biological sciences. Psychology
Hemostasis - drug effects
Heparin Antagonists - pharmacology
Humans
PBT-3
PFA-100
Platelet Aggregation - drug effects
Reference Values
Thromboxane antagonists
Vertebrates: blood, hematopoietic organs, reticuloendothelial system
Vertebrates: cardiovascular system
Whole blood
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ISSN:0049-3848
1879-2472
DOI:10.1016/j.thromres.2003.12.014