Two different biological configurations for long-term memory

• Published in: Neurobiology of learning and memory 2004, Vol.81 (1), p.12-18
• Main Authors: Epstein, Herman T., Kuzirian, Alan M., Child, Frank M., Alkon, Daniel L.
• Format: Article
• Language: English
• Subjects: Animals; Association Learning - drug effects; Association Learning - physiology; Avoidance Learning - drug effects; Avoidance Learning - physiology; Biochemistry. Physiology. Immunology; Biological and medical sciences; Cell Adhesion Molecules - antagonists & inhibitors; Cell Adhesion Molecules - physiology; Conditioning, Classical - drug effects; Conditioning, Classical - physiology; Consolidation; Dose-Response Relationship, Drug; Extracellular Matrix Proteins - antagonists & inhibitors; Extracellular Matrix Proteins - physiology; Fundamental and applied biological sciences. Psychology; Hermissenda; Invertebrates; Long-Term Potentiation - drug effects; Long-Term Potentiation - physiology; Memory stages; Mental Recall - drug effects; Mental Recall - physiology; Mollusca; Oligopeptides - pharmacology; Photoreceptor Cells, Invertebrate - drug effects; Photoreceptor Cells, Invertebrate - physiology; Physiology. Development; Recall; Retention; Retention (Psychology) - drug effects; Retention (Psychology) - physiology; Vestibule, Labyrinth - drug effects; Vestibule, Labyrinth - physiology
• ISSN: 1074-7427; 1095-9564
• DOI: 10.1016/S1074-7427(03)00074-1

Long-term memory (LTM) in Hermissenda can be distinguished from consolidated long-term memory (CLTM) by determining how long recall is retained. LTM is retained for approximately 1 day, while CLTM is retained for at least 3 days. During the transition from LTM to CLTM, the extent of retention appears to depend partially on how much consolidation has been completed. Several models are discussed that may be related to the two different manifestations of recall.