Cardiovascular risk in dialysis patients: A comparison of risk factors and cardioprotective therapy between 1996 and 2001

Cardiovascular disease (CVD) is the major cause of mortality in dialysis patients. Aspirin, beta‐blockers, statins, and angiotensin‐converting enzyme (ACE) inhibitors reduce CVD mortality in the general population, as may angiotensin II receptor antagonists. The prevalence of cardiovascular risk fac...

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Bibliographic Details
Published in:Nephrology (Carlton, Vic.) Vic.), 2003-08, Vol.8 (4), p.177-183
Main Authors: CHOW, Fiona YF, POLKINGHORNE, Kevan R, CHADBAN, Steven J, ATKINS, Robert C, KERR, Peter G
Format: Article
Language:English
Subjects:
Cardiotonic Agents - therapeutic use
cardiovascular disease
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - etiology
Cardiovascular Diseases - prevention & control
chronic renal failure
Cross-Sectional Studies
diabetes
Female
Humans
hyperlipidaemia
hypertension
Male
Middle Aged
Prevalence
Renal Dialysis - adverse effects
Retrospective Studies
Risk Factors
smoking
Survival Analysis
Survival Rate
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Summary:Cardiovascular disease (CVD) is the major cause of mortality in dialysis patients. Aspirin, beta‐blockers, statins, and angiotensin‐converting enzyme (ACE) inhibitors reduce CVD mortality in the general population, as may angiotensin II receptor antagonists. The prevalence of cardiovascular risk factors and usage rates of cardioprotective agents in end‐stage renal failure are unknown. A retrospective, cross‐sectional study of dialysis patients was performed to compare: (i) prevalence of cardiovascular risk factors (age, hypertension, hyperlipidaemia, diabetes mellitus, and smoking); (ii) use of cardioprotective agents; and (iii) prevalence of cardiovascular disease between the time‐points: 1996 (n = 262) versus 2001 (n = 369). We found an increase in the risk factors of age (53.6 ± 14.9 years in 1996 vs 58.4 ± 14.3 in 2001; P 
ISSN:1320-5358
1440-1797
DOI:10.1046/j.1440-1797.2003.00157.x