Oral lichen planus and hepatitis C virus infection

OBJECTIVE: This investigation was conducted to determine the possible association between oral lichen planus (OLP) and hepatitis C virus infection (HCV) in the population of São Paulo (Brazil). MATERIALS AND METHODS: Three groups of patients were studied: group 1 was composed of 68 patients with OLP...

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Bibliographic Details
Published in:Oral diseases 2002-01, Vol.8 (1), p.42-46
Main Authors: Figueiredo, LC, Carrilho, FJ, De Andrade, HF, Migliari, DA
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Distribution
Aged
Biological and medical sciences
Brazil - epidemiology
Case-Control Studies
Chi-Square Distribution
Dentistry
Female
Hepatitis C - complications
Hepatitis C - epidemiology
hepatitis C infection
Hepatitis C virus
Human viral diseases
Humans
Infectious diseases
lichen planus
Lichen Planus, Oral - complications
Lichen Planus, Oral - epidemiology
liver disease
Male
Medical sciences
Middle Aged
Non tumoral diseases
oral
Otorhinolaryngology. Stomatology
Prevalence
Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
Viral diseases
Viral hepatitis
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Summary:OBJECTIVE: This investigation was conducted to determine the possible association between oral lichen planus (OLP) and hepatitis C virus infection (HCV) in the population of São Paulo (Brazil). MATERIALS AND METHODS: Three groups of patients were studied: group 1 was composed of 68 patients with OLP lesions; group 2 had 126 patients with HCV infection; and the control group consisted of 898 individuals seeking dental treatment at our school, used to determine the prevalence of lichen planus in the general population. The prevalence of HCV in group 1 was determined and compared with that of the population of São Paulo (Focaccia et al (1998) Brazilian J Infec Dis 2: 269), while the prevalence of OLP in group 2 was determined and compared with that of the control group. RESULTS: The results showed that the frequency of HCV in OLP patients was 8.8%, significantly higher than in the general population of São Paulo, which is 1.4% (P=0.002), and the frequency of OLP in HCV patients (4.7%) was also significantly higher (P=0.0003) than that of the control group (0.6%). CONCLUSION: These data suggest that, at least in São Paulo, there is an association between OLP and HCV infection.
ISSN:1354-523X
1601-0825
DOI:10.1034/j.1601-0825.2002.10763.x