Sex Hormones, Neurotransmitters, and Psychopharmacological Treatments in Men with Paraphilic Disorders

Paraphilic disorders are psychiatric syndromes primarily characterized by deviant sexual thoughts, cravings, urges, and/or behaviors. Paraphilic men may engage in inappropriate sexual behaviors when cravings for socially unacceptable sexual acts become overpowering. These often chronic disorders may...

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Bibliographic Details
Published in:Journal of child sexual abuse 2003, Vol.12 (3-4), p.233-253
Main Authors: Saleh, Fabian M., Berlin, Fred S.
Format: Article
Language:English
Subjects:
Adult
Androgen Antagonists - therapeutic use
Antisocial Behavior
Biochemistry
Cyproterone Acetate - therapeutic use
Dose-Response Relationship, Drug
Drug Therapy
Forensic Psychiatry - methods
Hormones
Humans
Leuprolide - therapeutic use
Male
Males
Medroxyprogesterone - therapeutic use
Men
Mental Disorders
Neurological Organization
Neurotransmitters
Paraphiliacs
Paraphilias
Paraphilic Disorders - drug therapy
Paraphilic Disorders - physiopathology
Paraphilic Disorders - psychology
Pharmacology
pharmacotherapy
Serotonin reuptake inhibitors
Sex offenders
Sex Offenses - prevention & control
Sex Offenses - psychology
Sexual Abuse
Sexual Behavior - drug effects
Sexual Behavior - psychology
Sexual disorders
Sexuality
Testosterone
Testosterone - metabolism
USA
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Summary:Paraphilic disorders are psychiatric syndromes primarily characterized by deviant sexual thoughts, cravings, urges, and/or behaviors. Paraphilic men may engage in inappropriate sexual behaviors when cravings for socially unacceptable sexual acts become overpowering. These often chronic disorders may not only cause emotional distress and social embarrassment to the afflicted patient but also to the targets of their paraphilic focus. The primary objective of this article is to examine and review data on the efficacy and tolerability of the testosterone-lowering agents medroxprogesterone acetate, cyproterone acetate, and leuprolide acetate. The secondary goal is to review data on less conventional and more innovative pharmacological treatments, particularly the serotonin-specific reuptake inhibitors.
ISSN:1053-8712
1547-0679
DOI:10.1300/J070v12n03_09