Iodine deficiency in Calabria: Characterization of endemic goiter and analysis of different indicators of iodine status region-wide

The distribution of goiter prevalence in schoolchildren (no.=13,984, age 6-14 yr), the neonatal TSH results obtained from the congenital hypothyroidism screening program and the urinary iodine excretion values (no.=284) were employed for the assessment of iodine deficiency in Calabria, a Southern It...

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Bibliographic Details
Published in:Journal of endocrinological investigation 2002-03, Vol.25 (3), p.201-207
Main Authors: COSTANTE, G, GRASSO, L, FILETTI, S, SCHIFINO, E, MARASCO, M. F, CROCETTI, U, CAPULA, C, CHIARELLA, R, LUDOVICO, O, NOCERA, M, PARLATO, G
Format: Article
Language:English
Subjects:
Adolescent
Age Factors
Analysis. Health state
Biological and medical sciences
Child
Congenital Hypothyroidism
Endemic Diseases
Endocrinopathies
Epidemiology
Female
General aspects
Goiter - epidemiology
Humans
Hypothyroidism - diagnosis
Infant, Newborn
Iodine - deficiency
Iodine - urine
Male
Medical sciences
Neonatal Screening
Non tumoral diseases. Target tissue resistance. Benign neoplasms
Nutritional Status
Public health. Hygiene
Public health. Hygiene-occupational medicine
Sex Factors
Thyroid. Thyroid axis (diseases)
Thyrotropin - blood
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Summary:The distribution of goiter prevalence in schoolchildren (no.=13,984, age 6-14 yr), the neonatal TSH results obtained from the congenital hypothyroidism screening program and the urinary iodine excretion values (no.=284) were employed for the assessment of iodine deficiency in Calabria, a Southern Italy region. Data were collected during the years 1990-1996. In the inland territory, goiter prevalence ranged from 19 to 64%. At sea level, there was a great variability of goiter prevalence, with values varying from 5.3 to 25.7%. The analysis of the neonatal hypothyroidism screening program data (no.=21,078) showed a 14.8% frequency of TSH levels >5 microU/ml whole blood in newborns from the inland territory and a 14.1% frequency at sea level. Urinary iodine excretion resulted (mean+/-SD) 53.8+/-43.4 microg/l (range:
ISSN:0391-4097
1720-8386
DOI:10.1007/BF03343991