Twenty-four hour pH monitoring during pregnancy and at postpartum: a preliminary study

Objective: To quantify the amount of acid refluxed in symptomatic pregnant women and compare this to the postpartum period. Methods: Eight non complicated symptomatic pregnant women were enrolled. The mean age was 28±6.3 years and gestational age 26±4.4 weeks at inclusion. Repeated measurements were...

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Bibliographic Details
Published in:European journal of obstetrics & gynecology and reproductive biology 2002-05, Vol.102 (2), p.127-130
Main Author: Al Amri, Saleh Mohsen
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biological and medical sciences
Deglutition Disorders
Esophageal sphincter pressure
Esophagogastric Junction - physiopathology
Female
Gastroenterology. Liver. Pancreas. Abdomen
Gastroesophageal Reflux - complications
Gastroesophageal Reflux - diagnosis
Gastroesophageal Reflux - physiopathology
Gastroesophageal reflux disease
Gestational Age
Heartburn
Humans
Hydrogen-Ion Concentration
Medical sciences
Monitoring, Physiologic
Other diseases. Semiology
Postpartum
Pregnancy
Pregnancy Complications
Pressure
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
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Summary:Objective: To quantify the amount of acid refluxed in symptomatic pregnant women and compare this to the postpartum period. Methods: Eight non complicated symptomatic pregnant women were enrolled. The mean age was 28±6.3 years and gestational age 26±4.4 weeks at inclusion. Repeated measurements were done at 9.8±6.5 weeks postpartum. Esophageal manometry and 24 h pH monitoring were performed at each time period. Results: Heartburn (HB), regurgitation and dysphagia were the main presenting symptoms, however only regurgitation was significantly more frequent during pregnancy ( P=0.01). Lower esophageal sphincter (LES) pressure was significantly lower during pregnancy ( P=0.001). Twenty-four hour pH monitoring variables were worse and the number of reflux episodes and the upright reflux reached statistical significance ( P=0.03, and 0.01, respectively). Conclusion: Pregnancy is associated with decreased LES pressure, more frequent episodes of reflux and upright reflux.
ISSN:0301-2115
1872-7654
DOI:10.1016/S0301-2115(01)00593-0