Color discrimination in schizophrenia

Neuropsychiatric conditions that involve dopaminergic depletion have been associated with color discrimination deficits along the blue-hue (tritan, or short-wavelength-sensitive) axis. Because dopamine dysregulation may be a major factor in schizophrenia, we investigated color vision in this disorde...

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Bibliographic Details
Published in:Schizophrenia research 2002-05, Vol.55 (1), p.197-204
Main Authors: Shuwairi, Sarah M., Cronin-Golomb, Alice, McCarley, Robert W., O'Donnell, Brian F.
Format: Article
Language:English
Subjects:
Adult
Adult and adolescent clinical studies
Biological and medical sciences
Chronic Disease
Color Perception - physiology
Color Perception Tests
Color vision
Color Vision Defects - diagnosis
Color Vision Defects - physiopathology
Discrimination Learning - physiology
Dopamine
Dopamine - physiology
Hue discrimination
Humans
Medical sciences
Middle Aged
Psychiatric Status Rating Scales
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychoses
Schizophrenia
Schizophrenia - diagnosis
Schizophrenia - physiopathology
Schizophrenic Psychology
Tritan (blue-hue)
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Summary:Neuropsychiatric conditions that involve dopaminergic depletion have been associated with color discrimination deficits along the blue-hue (tritan, or short-wavelength-sensitive) axis. Because dopamine dysregulation may be a major factor in schizophrenia, we investigated color vision in this disorder. The performance of males with schizophrenia (SZ, n=16) and normal male control subjects (CS, n=14) was evaluated on five measures of color discrimination. SZ made more hue discrimination errors than CS, but no pattern emerged regarding a hue-specific axis of deficit. Dosage of anti-psychotic medication was not correlated with performance on hue discrimination. These results suggest that in medicated patients with schizophrenia, the dopaminergic disturbance, which may involve system hyperactivity, does not produce tritan-specific color deficits that have been observed in disorders involving dopaminergic hypoactivity.
ISSN:0920-9964
1573-2509
DOI:10.1016/S0920-9964(01)00180-3