Modeling inferior olive neuron dynamics

A model for the study of the dynamic properties of inferior olive neuron is presented. The model, a dynamical system, comprises two autonomous components of minimal complexity that are capable of reproducing the large gamut of experimentally observed inferior olive neuron dynamics. The two autonomou...

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Bibliographic Details
Published in:Neural networks 2002, Vol.15 (1), p.5-10
Main Authors: Velarde, Manuel G., Nekorkin, Vladimir I., Kazantsev, Viktor B., Makarenko, Vladimir I., Llinás, Rodolfo
Format: Article
Language:English
Subjects:
Action Potentials - physiology
Autonomous components
High and low threshold spike generation
Humans
inferior olive
Inferior olive neuron
Membrane potential dynamics
Models, Neurological
Neurons - physiology
Olivary Nucleus - physiology
Oscillometry
Subthreshold oscillations
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Summary:A model for the study of the dynamic properties of inferior olive neuron is presented. The model, a dynamical system, comprises two autonomous components of minimal complexity that are capable of reproducing the large gamut of experimentally observed inferior olive neuron dynamics. The two autonomous parts are responsible for largely different aspects of the dynamic profile of the model. These include subthreshold oscillations and different modes (high and low threshold) of action potential generation.
ISSN:0893-6080
1879-2782
DOI:10.1016/S0893-6080(01)00130-7