Subepithelial Connective Tissue Graft for Root Coverage in Smokers and Non‐Smokers: A Clinical and Histologic Controlled Study in Humans

Background: The aim of this study was to evaluate root coverage of gingival recessions and to compare graft vascularization in smokers and non‐smokers. Methods: Thirty subjects, 15 smokers and 15 non‐smokers, were selected. Each subject had one Miller Class I or II recession in a non‐molar tooth. Cl...

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Bibliographic Details
Published in:Journal of periodontology (1970) 2008-06, Vol.79 (6), p.1014-1021
Main Authors: Souza, Sérgio L.S., Macedo, Guilherme O., Tunes, Roberta S., Silveira e Souza, Adriana M.M., Novaes, Arthur B., Grisi, Marcio F.M., Taba, Mário, Palioto, Daniela B., Correa, Vani M.A.
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Case-Control Studies
Connective tissue
Connective Tissue - blood supply
Connective Tissue - transplantation
Dentistry
Female
Gingival Recession - etiology
Gingival Recession - surgery
Gingivoplasty
grafts
Humans
Male
Medical sciences
Middle Aged
Neovascularization, Physiologic
plastic surgery
Smoking - adverse effects
Statistics, Nonparametric
Tobacco, tobacco smoking
Toxicology
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Summary:Background: The aim of this study was to evaluate root coverage of gingival recessions and to compare graft vascularization in smokers and non‐smokers. Methods: Thirty subjects, 15 smokers and 15 non‐smokers, were selected. Each subject had one Miller Class I or II recession in a non‐molar tooth. Clinical measurements of probing depth (PD), relative clinical attachment level (CAL), gingival recession (GR), and width of keratinized tissue (KT) were determined at baseline and 3 and 6 months after surgery. The recessions were treated surgically with a coronally positioned flap associated with a subepithelial connective tissue graft. A small portion of this graft was prepared for immunohistochemistry. Blood vessels were identified and counted by expression of factor VIII–related antigen–stained endothelial cells. Results: Intragroup analysis showed that after 6 months there a was gain in CAL, a decrease in GR, and an increase in KT for both groups (P
ISSN:0022-3492
1943-3670
DOI:10.1902/jop.2008.070479