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Continuous low-level heat wrap therapy provides more efficacy than ibuprofen and acetaminophen for acute low back pain
A prospective, randomized, single (investigator) blind, comparative efficacy trial was conducted. To compare the efficacy of continuous low-level heat wrap therapy (40 C, 8 hours/day) with that of ibuprofen (1200 mg/day) and acetaminophen (4000 mg/day) in subjects with acute nonspecific low back pai...
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| Published in: | Spine (Philadelphia, Pa. 1976) Pa. 1976), 2002-05, Vol.27 (10), p.1012-1017 |
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| container_end_page | 1017 |
| container_issue | 10 |
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| container_title | Spine (Philadelphia, Pa. 1976) |
| container_volume | 27 |
| creator | NADLER, Scott F STEINER, Deborah J ERASALA, Geetha N HENGEHOLD, David A HINKLE, Robert T GOODALE, Mary Beth ABELN, Susan B WEINGAND, Kurt W |
| description | A prospective, randomized, single (investigator) blind, comparative efficacy trial was conducted.
To compare the efficacy of continuous low-level heat wrap therapy (40 C, 8 hours/day) with that of ibuprofen (1200 mg/day) and acetaminophen (4000 mg/day) in subjects with acute nonspecific low back pain.
The efficacy of topical heat methods, as compared with oral analgesic treatment of low back pain, has not been established.
Subjects (n = 371) were randomly assigned to heat wrap (n = 113), acetaminophen (n = 113), or ibuprofen (n = 106) for efficacy evaluation, or to oral placebo (n = 20) or unheated back wrap (n = 19) for blinding. Outcome measures included pain relief, muscle stiffness, lateral trunk flexibility, and disability. Efficacy was measured over two treatment days and two follow-up days.
Day 1 pain relief for the heat wrap (mean, 2) was higher than for ibuprofen (mean, 1.51; P = 0.0007) or acetaminophen (mean, 1.32; P = 0.0001). Extended mean pain relief (Days 3 to 4) for the heat wrap (mean, 2.61) also was higher than for ibuprofen (mean, 1.68; P = 0.0001) or acetaminophen (mean, 1.95; P = 0.0009). Lateral trunk flexibility was improved with the heat wrap (mean change, 4.28 cm) during treatment (P |
| doi_str_mv | 10.1097/00007632-200205150-00003 |
| format | article |
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To compare the efficacy of continuous low-level heat wrap therapy (40 C, 8 hours/day) with that of ibuprofen (1200 mg/day) and acetaminophen (4000 mg/day) in subjects with acute nonspecific low back pain.
The efficacy of topical heat methods, as compared with oral analgesic treatment of low back pain, has not been established.
Subjects (n = 371) were randomly assigned to heat wrap (n = 113), acetaminophen (n = 113), or ibuprofen (n = 106) for efficacy evaluation, or to oral placebo (n = 20) or unheated back wrap (n = 19) for blinding. Outcome measures included pain relief, muscle stiffness, lateral trunk flexibility, and disability. Efficacy was measured over two treatment days and two follow-up days.
Day 1 pain relief for the heat wrap (mean, 2) was higher than for ibuprofen (mean, 1.51; P = 0.0007) or acetaminophen (mean, 1.32; P = 0.0001). Extended mean pain relief (Days 3 to 4) for the heat wrap (mean, 2.61) also was higher than for ibuprofen (mean, 1.68; P = 0.0001) or acetaminophen (mean, 1.95; P = 0.0009). Lateral trunk flexibility was improved with the heat wrap (mean change, 4.28 cm) during treatment (P </= 0.009 vs acetaminophen [mean change, 2.93 cm], P </= 0.001 vs ibuprofen [mean change, 2.51 cm]). The results were similar on Day 4. Day 1 reduction in muscle stiffness with the heat wrap (mean, 16.3) was greater than with acetaminophen (mean, 10.5; P = 0.001). Disability was reduced with the heat wrap (mean, 4.9), as compared with ibuprofen (mean, 2.7; P = 0.01) and acetaminophen (mean, 2.9; P = 0.0007), on Day 4. None of the adverse events were serious. The highest rate (10.4%) was reported in the ibuprofen group.
Continuous low-level heat wrap therapy was superior to both acetaminophen and ibuprofen for treating low back pain.</description><identifier>ISSN: 0362-2436</identifier><identifier>EISSN: 1528-1159</identifier><identifier>DOI: 10.1097/00007632-200205150-00003</identifier><identifier>PMID: 12004166</identifier><identifier>CODEN: SPINDD</identifier><language>eng</language><publisher>Philadelphia, PA: Lippincott</publisher><subject>Acetaminophen - therapeutic use ; Acute Disease ; Adolescent ; Adult ; Analgesics, Non-Narcotic - therapeutic use ; Biological and medical sciences ; Diseases of the osteoarticular system. Orthopedic treatment ; Female ; Follow-Up Studies ; Hot Temperature - therapeutic use ; Humans ; Ibuprofen - therapeutic use ; Low Back Pain - pathology ; Low Back Pain - therapy ; Male ; Medical sciences ; Middle Aged ; Muscle Cramp - therapy ; Prospective Studies ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) ; Severity of Illness Index ; Single-Blind Method ; Treatment Outcome</subject><ispartof>Spine (Philadelphia, Pa. 1976), 2002-05, Vol.27 (10), p.1012-1017</ispartof><rights>2002 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c436t-323ba47f5b431f67b9e5387ff2adc5d0c74deda58feb8543fdf0c2a2493ac7893</citedby><cites>FETCH-LOGICAL-c436t-323ba47f5b431f67b9e5387ff2adc5d0c74deda58feb8543fdf0c2a2493ac7893</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=13675830$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12004166$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>NADLER, Scott F</creatorcontrib><creatorcontrib>STEINER, Deborah J</creatorcontrib><creatorcontrib>ERASALA, Geetha N</creatorcontrib><creatorcontrib>HENGEHOLD, David A</creatorcontrib><creatorcontrib>HINKLE, Robert T</creatorcontrib><creatorcontrib>GOODALE, Mary Beth</creatorcontrib><creatorcontrib>ABELN, Susan B</creatorcontrib><creatorcontrib>WEINGAND, Kurt W</creatorcontrib><title>Continuous low-level heat wrap therapy provides more efficacy than ibuprofen and acetaminophen for acute low back pain</title><title>Spine (Philadelphia, Pa. 1976)</title><addtitle>Spine (Phila Pa 1976)</addtitle><description>A prospective, randomized, single (investigator) blind, comparative efficacy trial was conducted.
To compare the efficacy of continuous low-level heat wrap therapy (40 C, 8 hours/day) with that of ibuprofen (1200 mg/day) and acetaminophen (4000 mg/day) in subjects with acute nonspecific low back pain.
The efficacy of topical heat methods, as compared with oral analgesic treatment of low back pain, has not been established.
Subjects (n = 371) were randomly assigned to heat wrap (n = 113), acetaminophen (n = 113), or ibuprofen (n = 106) for efficacy evaluation, or to oral placebo (n = 20) or unheated back wrap (n = 19) for blinding. Outcome measures included pain relief, muscle stiffness, lateral trunk flexibility, and disability. Efficacy was measured over two treatment days and two follow-up days.
Day 1 pain relief for the heat wrap (mean, 2) was higher than for ibuprofen (mean, 1.51; P = 0.0007) or acetaminophen (mean, 1.32; P = 0.0001). Extended mean pain relief (Days 3 to 4) for the heat wrap (mean, 2.61) also was higher than for ibuprofen (mean, 1.68; P = 0.0001) or acetaminophen (mean, 1.95; P = 0.0009). Lateral trunk flexibility was improved with the heat wrap (mean change, 4.28 cm) during treatment (P </= 0.009 vs acetaminophen [mean change, 2.93 cm], P </= 0.001 vs ibuprofen [mean change, 2.51 cm]). The results were similar on Day 4. Day 1 reduction in muscle stiffness with the heat wrap (mean, 16.3) was greater than with acetaminophen (mean, 10.5; P = 0.001). Disability was reduced with the heat wrap (mean, 4.9), as compared with ibuprofen (mean, 2.7; P = 0.01) and acetaminophen (mean, 2.9; P = 0.0007), on Day 4. None of the adverse events were serious. The highest rate (10.4%) was reported in the ibuprofen group.
Continuous low-level heat wrap therapy was superior to both acetaminophen and ibuprofen for treating low back pain.</description><subject>Acetaminophen - therapeutic use</subject><subject>Acute Disease</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Analgesics, Non-Narcotic - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Diseases of the osteoarticular system. Orthopedic treatment</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Hot Temperature - therapeutic use</subject><subject>Humans</subject><subject>Ibuprofen - therapeutic use</subject><subject>Low Back Pain - pathology</subject><subject>Low Back Pain - therapy</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Muscle Cramp - therapy</subject><subject>Prospective Studies</subject><subject>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</subject><subject>Severity of Illness Index</subject><subject>Single-Blind Method</subject><subject>Treatment Outcome</subject><issn>0362-2436</issn><issn>1528-1159</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><recordid>eNpFkMtu2zAQRYmiReK4-YWCm3SnlA-RlJaF0TwAA9m0a2FEDWG2EqWSkgP_felEabgZ4M65M8NLCOXslrPafGP5GS1FIRgTTHHFirMkP5ANV6IqOFf1R7JhUmeklPqSXKX0OxNa8vqCXPLsK7nWG3LcjWH2YRmXRPvxuejxiD09IMz0OcJE5wPmcqJTHI--w0SHMSJF57wFe8ptCNS3S247DBRCR8HiDIMP43TIihtjVpYZz9NpC_YPncCHz-STgz7h9Vq35Nfdj5-7h2L_dP-4-74vbL56LqSQLZTGqbaU3GnT1qhkZZwT0FnVMWvKDjtQlcO2UqV0nWNWgChrCdZUtdySr69z84F_F0xzM_hkse8hYP5yY7g2XPAyg9UraOOYUkTXTNEPEE8NZ8058-Yt8-Z_5i-SzNYv646lHbB7N64hZ-BmBSBZ6F2EYH1656Q2qpJM_gOmJYu5</recordid><startdate>20020515</startdate><enddate>20020515</enddate><creator>NADLER, Scott F</creator><creator>STEINER, Deborah J</creator><creator>ERASALA, Geetha N</creator><creator>HENGEHOLD, David A</creator><creator>HINKLE, Robert T</creator><creator>GOODALE, Mary Beth</creator><creator>ABELN, Susan B</creator><creator>WEINGAND, Kurt W</creator><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20020515</creationdate><title>Continuous low-level heat wrap therapy provides more efficacy than ibuprofen and acetaminophen for acute low back pain</title><author>NADLER, Scott F ; STEINER, Deborah J ; ERASALA, Geetha N ; HENGEHOLD, David A ; HINKLE, Robert T ; GOODALE, Mary Beth ; ABELN, Susan B ; WEINGAND, Kurt W</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c436t-323ba47f5b431f67b9e5387ff2adc5d0c74deda58feb8543fdf0c2a2493ac7893</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Acetaminophen - therapeutic use</topic><topic>Acute Disease</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Analgesics, Non-Narcotic - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Diseases of the osteoarticular system. Orthopedic treatment</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Hot Temperature - therapeutic use</topic><topic>Humans</topic><topic>Ibuprofen - therapeutic use</topic><topic>Low Back Pain - pathology</topic><topic>Low Back Pain - therapy</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Muscle Cramp - therapy</topic><topic>Prospective Studies</topic><topic>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</topic><topic>Severity of Illness Index</topic><topic>Single-Blind Method</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>NADLER, Scott F</creatorcontrib><creatorcontrib>STEINER, Deborah J</creatorcontrib><creatorcontrib>ERASALA, Geetha N</creatorcontrib><creatorcontrib>HENGEHOLD, David A</creatorcontrib><creatorcontrib>HINKLE, Robert T</creatorcontrib><creatorcontrib>GOODALE, Mary Beth</creatorcontrib><creatorcontrib>ABELN, Susan B</creatorcontrib><creatorcontrib>WEINGAND, Kurt W</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Spine (Philadelphia, Pa. 1976)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>NADLER, Scott F</au><au>STEINER, Deborah J</au><au>ERASALA, Geetha N</au><au>HENGEHOLD, David A</au><au>HINKLE, Robert T</au><au>GOODALE, Mary Beth</au><au>ABELN, Susan B</au><au>WEINGAND, Kurt W</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Continuous low-level heat wrap therapy provides more efficacy than ibuprofen and acetaminophen for acute low back pain</atitle><jtitle>Spine (Philadelphia, Pa. 1976)</jtitle><addtitle>Spine (Phila Pa 1976)</addtitle><date>2002-05-15</date><risdate>2002</risdate><volume>27</volume><issue>10</issue><spage>1012</spage><epage>1017</epage><pages>1012-1017</pages><issn>0362-2436</issn><eissn>1528-1159</eissn><coden>SPINDD</coden><abstract>A prospective, randomized, single (investigator) blind, comparative efficacy trial was conducted.
To compare the efficacy of continuous low-level heat wrap therapy (40 C, 8 hours/day) with that of ibuprofen (1200 mg/day) and acetaminophen (4000 mg/day) in subjects with acute nonspecific low back pain.
The efficacy of topical heat methods, as compared with oral analgesic treatment of low back pain, has not been established.
Subjects (n = 371) were randomly assigned to heat wrap (n = 113), acetaminophen (n = 113), or ibuprofen (n = 106) for efficacy evaluation, or to oral placebo (n = 20) or unheated back wrap (n = 19) for blinding. Outcome measures included pain relief, muscle stiffness, lateral trunk flexibility, and disability. Efficacy was measured over two treatment days and two follow-up days.
Day 1 pain relief for the heat wrap (mean, 2) was higher than for ibuprofen (mean, 1.51; P = 0.0007) or acetaminophen (mean, 1.32; P = 0.0001). Extended mean pain relief (Days 3 to 4) for the heat wrap (mean, 2.61) also was higher than for ibuprofen (mean, 1.68; P = 0.0001) or acetaminophen (mean, 1.95; P = 0.0009). Lateral trunk flexibility was improved with the heat wrap (mean change, 4.28 cm) during treatment (P </= 0.009 vs acetaminophen [mean change, 2.93 cm], P </= 0.001 vs ibuprofen [mean change, 2.51 cm]). The results were similar on Day 4. Day 1 reduction in muscle stiffness with the heat wrap (mean, 16.3) was greater than with acetaminophen (mean, 10.5; P = 0.001). Disability was reduced with the heat wrap (mean, 4.9), as compared with ibuprofen (mean, 2.7; P = 0.01) and acetaminophen (mean, 2.9; P = 0.0007), on Day 4. None of the adverse events were serious. The highest rate (10.4%) was reported in the ibuprofen group.
Continuous low-level heat wrap therapy was superior to both acetaminophen and ibuprofen for treating low back pain.</abstract><cop>Philadelphia, PA</cop><cop>Hagerstown, MD</cop><pub>Lippincott</pub><pmid>12004166</pmid><doi>10.1097/00007632-200205150-00003</doi><tpages>6</tpages></addata></record> |
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| identifier | ISSN: 0362-2436 |
| ispartof | Spine (Philadelphia, Pa. 1976), 2002-05, Vol.27 (10), p.1012-1017 |
| issn | 0362-2436 1528-1159 |
| language | eng |
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| source | LWW_医学期刊 |
| subjects | Acetaminophen - therapeutic use Acute Disease Adolescent Adult Analgesics, Non-Narcotic - therapeutic use Biological and medical sciences Diseases of the osteoarticular system. Orthopedic treatment Female Follow-Up Studies Hot Temperature - therapeutic use Humans Ibuprofen - therapeutic use Low Back Pain - pathology Low Back Pain - therapy Male Medical sciences Middle Aged Muscle Cramp - therapy Prospective Studies Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Severity of Illness Index Single-Blind Method Treatment Outcome |
| title | Continuous low-level heat wrap therapy provides more efficacy than ibuprofen and acetaminophen for acute low back pain |
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