Effects of exercise training on aerobic and functional capacity of end-stage renal disease patients

• Published in: Clinical physiology and functional imaging 2002-03, Vol.22 (2), p.115-124
• Main Authors: Koufaki, Pelagia, Mercer, Thomas H., Naish, Patrick F.
• Format: Article
• Language: English
• Subjects: Adaptation, Physiological - physiology; Adult; Aged; Biological and medical sciences; Exercise - physiology; Exercise Test; Exercise Therapy; Female; Follow-Up Studies; Humans; Kidney Failure, Chronic - physiopathology; Kidney Failure, Chronic - rehabilitation; Kidney Failure, Chronic - therapy; Male; Medical sciences; Middle Aged; Nephrology. Urinary tract diseases; Nephropathies. Renovascular diseases. Renal failure; Oxygen Consumption - physiology; rehabilitation; Renal failure; VO2 kinetics; VO2 peak
• ISSN: 1475-0961; 1475-097X
• DOI: 10.1046/j.1365-2281.2002.00405.x

The aim was to assess the effects of exercise training on aerobic and functional capacity of patients with end‐stage renal disease (ESRD). Patients completed an incremental exercise test on a cycle ergometer to determine VO2 peak and VO2 at ventilatory threshold (VT; V‐slope). On a separate day they performed two constant load exercise tests on a cycle ergometer at 90% of VT and at a workload of 33 W, to determine VO2 kinetics. Functional capacity was assessed using measurements of sit‐to‐stands (STS‐5, STS‐60) and a walk test. Dialysis patients were randomly allocated to an exercise (ET: n=18, age=57·3 years) or control (C: n=15, age=50·5 years) group. The ET group participated in an exercise training programme involving cycling for 3 months. Repeated measures ANOVA revealed significant time by group interactions (P